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Merck

GF171

Endostatin Protein, Human Recombinant

The Endostatin protein is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen.

Synonym(s):

Collagen Type XVIII, Collagen alpha-1 (XVIII)

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.75
eCl@ss:
32160405
Assay:
>98% (SDS-PAGE and HPLC)
Recombinant:
expressed in E. coli

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Product Name

Endostatin Protein, Human Recombinant, The Endostatin protein is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen.

recombinant

expressed in E. coli

assay

>98% (SDS-PAGE and HPLC)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

UniProt accession no.

P39060

shipped in

dry ice

Quality Level

100

Related Categories

Analysis Note

Bioactivity assay: Measured by its ability to inhibit HUVEC migration.

Application

Research Category
Stem Cell Research
Research Sub Category
Growth Factors & Receptors

Biochem/physiol Actions

Cross Reactivty
None

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant human Endostatin is a 20.2 kDa protein consisting 184 amino acid residues.
Product Source: E. coli.

Physical form

Product is filtered through a 0.2 micron filter before lyophilization.

Preparation Note

Store at -20°C for up to 6 months from date of receipt.

Storage Class

11 - Combustible Solids

wgk

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
GF17104053252691362

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