Skip to Content
Merck

FCMAB250A4

Milli-Mark® Anti-Bcl-2 Antibody, Alexa Fluor™488, clone AW604

clone AW604, Milli-Mark®, from mouse

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Milli-Mark® Anti-Bcl-2 Antibody, Alexa Fluor™488, clone AW604, clone AW604, Milli-Mark®, from mouse

biological source

mouse

conjugate

ALEXA FLUOR™ 488

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

AW604, monoclonal

species reactivity

human

manufacturer/tradename

Milli-Mark®

technique(s)

flow cytometry: suitable

isotype

IgG2a

NCBI accession no.

NP_000624

UniProt accession no.

P10415

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... BCL2(596)

Related Categories

Analysis Note

Control
Jurkat Cells
Evaulated by flow cytometery using Jurkat cells.

Application

Research Category
Apoptosis & Cancer
Research Sub Category
BCL2 & Inhibition
This Milli-Mark Bcl-2 antibody is validated for use in Flow for the detection of the Milli-Mark Bcl-2 protein.

Biochem/physiol Actions

Antibody recognizes Bcl-2.

Disclaimer

Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.

General description

26 kDa Calculated
Bcl-2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Bcl-2 also regulates cell death by controlling the mitochondrial membrane permeability and appears to function in a feedback loop system with caspases. It appears to Inhibit caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Further understanding in how Bcl-2 functions and interacts with other proteins to promote or inhibit apoptosis may lead to new treatments for cancer, neurological disorders and autoimmune diseases.

Immunogen

KLH-conjugated, synthetic peptide corresponding to human Bcl-2

Physical form

Protein G Purified
Purified mouse monoclonal IgG2a conjugated to Alexa Fluor™ 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Preparation Note

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKUGTIN
FCMAB250A404053252290091

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service