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676474 VEGF₁₆₄, Mouse, Recombinant, S. frugiperda

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676474
  
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      Overview

      Replacement Information

      Key Spec Table

      Purity
      ≥95% by SDS-PAGE
      Description
      Overview

      This product has been discontinued.



      Recombinant, mouse VEGF164 (164-amino acid splice variant of VEGF) expressed in S. frugiperda insect cells. The most abundant form in mice, VEGF164 is a potent angiogenic factor and vascular permeability factor in vivo, as well as a chemoattractant for monocytes and endothelial cells. Forms a biologically active homodimer and evidence suggests that it is also biologically active as a heterodimer with other VEGF splice variants. Expression of VEGF164 appears to be essential for normal bone development and vascularization.

      Catalogue Number676474
      Brand Family Calbiochem®
      SynonymsVascular Endothelial Growth Factor₁₆₄
      References
      ReferencesMaes, C., et al. 2002. Mech. Dev. 111, 61.
      Grunstein, J., et al. 2000. Mol. Cell Biol. 20, 7282.
      Springer, M.L., et al. 2000. J. Gene Med. 2, 279.
      Product Information
      FormLyophilized solid
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ ≥1 ng/ml as measured by the stimulation of ³H-thymidine incorporation by human umbilical vein endothelial cells and bovine aortic endothelial cells. In vivo effects using the 13-day-old chick chorioallantoic membrane (CAM) assay can be seen between 0.5-4 µg
      Purity≥95% by SDS-PAGE
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      676474 0

      Documentation

      VEGF₁₆₄, Mouse, Recombinant, S. frugiperda MSDS

      Title

      Safety Data Sheet (SDS) 

      VEGF₁₆₄, Mouse, Recombinant, S. frugiperda Certificates of Analysis

      TitleLot Number
      676474

      References

      Reference overview
      Maes, C., et al. 2002. Mech. Dev. 111, 61.
      Grunstein, J., et al. 2000. Mol. Cell Biol. 20, 7282.
      Springer, M.L., et al. 2000. J. Gene Med. 2, 279.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision16-September-2008 RFH
      SynonymsVascular Endothelial Growth Factor₁₆₄
      DescriptionRecombinant, mouse VEGF164 (164-amino acid splice variant of VEGF) expressed in S. frugiperda insect cells. It is the most abundant form of VEGF found in mice. VEGF164 is a potent angiogenic factor and vascular permeability factor in vivo, as well as a chemoattractant for monocytes and endothelial cells. Forms a biological active homodimer. Evidence also suggests that it is biologically active as a heterodimer with other VEGF splice variants.
      FormLyophilized solid
      Purity≥95% by SDS-PAGE
      Biological activityED₅₀ ≥1 ng/ml as measured by the stimulation of ³H-thymidine incorporation by human umbilical vein endothelial cells and bovine aortic endothelial cells. In vivo effects using the 13-day-old chick chorioallantoic membrane (CAM) assay can be seen between 0.5-4 µg
      SolubilityReconstitute in PBS or 50 mM acetic acid to a concentration ≥ 100 ng/µl.
      Storage ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.
      Toxicity Standard Handling
      ReferencesMaes, C., et al. 2002. Mech. Dev. 111, 61.
      Grunstein, J., et al. 2000. Mol. Cell Biol. 20, 7282.
      Springer, M.L., et al. 2000. J. Gene Med. 2, 279.