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552233 QX-314 - CAS 21306-56-9 - Calbiochem

A quaternary lidocaine derivative, permanently charged, and lipophobic.

QX-314 - CAS 21306-56-9 - Calbiochem: Malzeme Güvenlik Bilgi Formu (MSDS) veya SDS, Analiz Sertifikası (COA) ve Kalite Uygunluk Sertifikası (COQ), dosyalar, broşürler ve diğer dokümanlar.
Primary Target: A powerful blocker of voltage-sensitive Na+ conductance
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552233
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Overview

Key Spec Table

CAS #Empirical Formula
21306-56-9C₁₆H₂₇BrN₂O

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
552233-100MG
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      Description
      OverviewA quaternary lidocaine derivative, permanently charged, and lipophobic. A powerful blocker of voltage-sensitive Na+ conductance when applied intracellularly. Suppresses the generation of Na+-dependent spikes from inside the cell membrane, without affecting Ca2+ currents or glutamate-activated currents.
      Catalogue Number552233
      Brand Family Calbiochem®
      References
      ReferencesMooney, R. 1992. J. Neurosci. 12, 2464.
      Regehr, W.G. and Tank, D.W. 1992. J. Neurosci. 12, 4202.
      Product Information
      CAS number21306-56-9
      ATP CompetitiveN
      FormLyophilized solid
      Hill FormulaC₁₆H₂₇BrN₂O
      Chemical formulaC₁₆H₂₇BrN₂O
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Biological activityfully active in neurophysiological testing
      Primary TargetA powerful blocker of voltage-sensitive Na+ conductance
      Purity≥99%
      Physicochemical Information
      Cell permeableN
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 weeks at 4°C.
      Global Trade Item Number
      Catalogue Number GTIN
      552233-100MG 04055977268331