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495455 Oligomycin - CAS 1404-19-9 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
1404-19-9C₄₅H₇₄O₁₁

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495455-10MG
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      Description
      OverviewA mixture of A, B, and C isomers. A macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase, preventing phosphoryl group transfer. Induces apoptosis in cultured human lymphoblastoid and other mammalian cells.
      Catalogue Number495455
      Brand Family Calbiochem®
      References
      ReferencesWolvetang, E.J., et al. 1994. FEBS Lett. 339, 40.
      Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther. 264, 515.
      Brustovetsky, N.N., et al. 1993. FEBS Lett. 315, 233.
      Nagamune, H., et al. 1993. Biochim. Biophys. Acta 1141, 231.
      Product Information
      CAS number1404-19-9
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₄₅H₇₄O₁₁
      Chemical formulaC₄₅H₇₄O₁₁
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetMembrane-bound mitochondrial ATPase (F1)
      Purity≥90% by HPLC (mixture of A, B, and C isomers)
      Physicochemical Information
      Cell permeableN
      Safety Information according to GHS
      RTECSRK3325000
      Safety Information
      R PhraseR: 36/38

      Irritating to eyes and skin.
      S PhraseS: 26

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 2 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      495455-10MG 04055977199734