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The following MAPmates™ should not be plexed together: -MAPmates™ that require a different assay buffer -Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9) -PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701) -More than 1 phospho-MAPmate™ for a single target (Akt, STAT3) -GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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NDSB-221: Malzeme Güvenlik Bilgi Formu (MSDS) veya SDS, Analiz Sertifikası (COA) ve Kalite Uygunluk Sertifikası (COQ), dosyalar, broşürler ve diğer dokümanlar.
A non-detergent sulfobetaine useful for the renaturation of unfolded proteins. At 1.8 M, NDSB-221 yields about 35% in native hen egg white lysozyme (HEWL), which is about 10-fold higher than in the absence of NDSB-221. At about 1.5 M, NDSB-221 efficiently increases the renaturation of β-D-galactosidase.
Catalogue Number
480014
Brand Family
Calbiochem®
Synonyms
3-(1-Methylpiperidinium)-1-propane Sulfonate
References
References
Goldberg, M.E., et al. 1996. Folding & Design1, 21.
Product Information
CAS number
160788-56-7
Form
White solid
Hill Formula
C₉H₁₉NO₃S
Chemical formula
C₉H₁₉NO₃S
Hygroscopic
Hygroscopic
Structure formula Image
Applications
Biological Information
Purity
≥95% by TLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R Phrase
R: 36/37/38
Irritating to eyes, respiratory system and skin.
S Phrase
S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code
Ambient Temperature Only
Toxicity
Irritant
Storage
+15°C to +30°C
Hygroscopic
Hygroscopic
Do not freeze
Ok to freeze
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number
GTIN
480014
0
Documentation
NDSB-221 Certificates of Analysis
Title
Lot Number
480014
References
Reference overview
Goldberg, M.E., et al. 1996. Folding & Design1, 21.
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
13-April-2011 RFH
Synonyms
3-(1-Methylpiperidinium)-1-propane Sulfonate
Description
A member of the class of nondetergent sulfobetaines. Unlike CHAPS and other zwittergents, which are also sulfobetaines, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range. They prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis. NDSB-221 at 1.8 M yields about 35% in native hen egg white lysozyme (HEWL), which is about 10-fold higher than in the absence of NDSB-221. At about 1.5 M, NDSB-221 efficiently increases the renaturation of β-D-galactosidase.
Form
White solid
CAS number
160788-56-7
Chemical formula
C₉H₁₉NO₃S
Structure formula
Purity
≥95% by TLC
Solubility
H₂O (100 mg/ml)
Storage
+15°C to +30°C
Hygroscopic
Do Not Freeze
Ok to freeze
Toxicity
Irritant
References
Goldberg, M.E., et al. 1996. Folding & Design1, 21.
