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HRNKLMAG-51K-01 MILLIPLEX MAP Human RANKL Magnetic Bead- Single Plex - Metabolism Assay

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HRNKLMAG-51K-01
96-well plate  
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      Overview

      Replacement Information

      Key Spec Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      RANKL HMplexLuminex xMAP
      Description
      Catalogue NumberHRNKLMAG-51K-01
      Trade Name
      • MILLIPLEX
      DescriptionMILLIPLEX MAP Human RANKL Magnetic Bead- Single Plex - Metabolism Assay
      Background InformationBone metabolism is the dynamic process of ongoing bone deposition and re-absorption, controlled by osteoblasts, osteocytes, and osteoclasts. While osteoblasts and osteocytes (osteoblasts surrounded by matrix) are responsible for bone deposition, osteoclasts are responsible for bone resorption. Both are required to maintain bone structure, as well as an adequate supply of calcium. To maintain this metabolic balance these cells rely on complex signaling pathways involving hormones and cytokines to achieve the appropriate rates of growth and differentiation.

      One of these proteins, Receptor Activator for Nuclear Factor B Ligand (RANKL) activates osteoclasts and has been implicated in degenerative bone diseases such as rheumatoid arthritis and osteomyelitis.
      References
      Product Information
      Detection methodLuminex xMAP
      ConfigurationSingle Plex
      Precision, %
      • Inter-assay: <15
      • Intra-assay: <10
      Panel TypeMAGNETIC Bone
      Quality LevelMQ200
      Applications
      ApplicationThis MILLIPLEX MAP Human RANKL Magnetic Bead- Single Plex, HRNKLMAG-51K-01 is a Metabolism single plex assay. The analyte available for this kit is RANKL.
      Key Applications
      • Multiplexing
      Application Notes• Same day or overnight incubation (recommended)
      • Samples can be run neat or diluted 1:2 (recommended) for human serum, plasma and tissue culture supernatants (25uL/well)
      Biological Information
      Species Reactivity
      • Human
      Analytes Available
      • RANKL
      Assay PanelEverything you need in a single kit.
      UniProt Number
      Accuracy
      • 92%
      Physicochemical Information
      Sensitivity
      • 5.0 pg/mL
      Linearity of DilutionContact technical support for information.
      Standard Curve Range
      • 4.88-20,000 pg/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size96-well plate
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      HRNKLMAG-51K-01 04055977289060