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440345 Lysozyme, Human Neutrophil

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440345
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440345-1MG
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      Description
      OverviewNative lysozyme from human neutrophils. Occurs in specific granules of human polymorphonuclear leukocytes and takes part in antibacterial activity of leukocytes. Hydrolyzes β1,4 linkages between N-acetylmuramic acid (2-acetamido-2-deoxy-3-O-[1′-carboxymethyl]-glucopyranose) residues in chitin.
      Catalogue Number440345
      Brand Family Calbiochem®
      SynonymsN-Acetylmuramyl Hydrolase, Muramidase
      References
      ReferencesLollike, K., et al. 1995. Leukemia 9, 206.
      Gordon, L.I., et al. 1979. J. Clin. Invest. 64, 226.
      Product Information
      CAS number9001-63-2
      Unit of DefinitionOne Shugar unit is defined as the amount of enzyme that will cause a decrease in absorbance of 0.001 at 450 nm per min due to lysis of <i>Micrococcus lysodeikticus</i> at 37°C, pH 7.0.
      EC number3.2.1.17
      FormLyophilized
      FormulationLyophilized from 100 mM NaCl, 50 mM sodium acetate buffer, pH 6.0.
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      SourcePrepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Specific Activity≥ 30,000 shugar units/mg protein
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSOL5987000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 3 days at 4°C or for up to 1 year at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      440345-1MG 04055977205954

      Documentation

      Lysozyme, Human Neutrophil MSDS

      Title

      Safety Data Sheet (SDS) 

      Lysozyme, Human Neutrophil Certificates of Analysis

      TitleLot Number
      440345

      References

      Reference overview
      Lollike, K., et al. 1995. Leukemia 9, 206.
      Gordon, L.I., et al. 1979. J. Clin. Invest. 64, 226.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision14-November-2013 JSW
      SynonymsN-Acetylmuramyl Hydrolase, Muramidase
      DescriptionNative lysozyme from human neutrophils. Occurs in specific granules of human polymorphonuclear leukocytes and takes part in antibacterial activity of leukocytes. Hydrolyzes β1,4-linkages between N-acetylmuramic acid (2-acetamido-2-deoxy-3-O-[1'-carboxymethyl]-glucopyranose) residues in chitin.
      FormLyophilized
      FormulationLyophilized from 100 mM NaCl, 50 mM sodium acetate buffer, pH 6.0.
      SourcePrepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      CAS number9001-63-2
      RTECSOL5987000
      EC number3.2.1.17
      Purity≥95% by SDS-PAGE
      Specific activity≥ 30,000 shugar units/mg protein
      Unit definitionOne Shugar unit is defined as the amount of enzyme that will cause a decrease in absorbance of 0.001 at 450 nm per min due to lysis of Micrococcus lysodeikticus at 37°C, pH 7.0.
      SolubilityAqueous Buffers or H₂O
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 3 days at 4°C or for up to 1 year at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 5640
      ReferencesLollike, K., et al. 1995. Leukemia 9, 206.
      Gordon, L.I., et al. 1979. J. Clin. Invest. 64, 226.