Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together: -MAPmates™ that require a different assay buffer -Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9) -PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701) -More than 1 phospho-MAPmate™ for a single target (Akt, STAT3) -GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
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48-602MAG
Buffer Detection Kit for Magnetic Beads
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Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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508162
Sigma-AldrichLoperamide Hydrochloride - CAS 34552-83-5 - Calbiochem
Loperamide Hydrochloride - CAS 34552-83-5 - Calbiochem: Malzeme Güvenlik Bilgi Formu (MSDS) veya SDS, Analiz Sertifikası (COA) ve Kalite Uygunluk Sertifikası (COQ), dosyalar, broşürler ve diğer dokümanlar.
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Description
Overview
A very potent and highly selective peripheral resctricted µ-opioid receptor agonist (Ki = 2 nM). Often used as an antidiarrheal, antipruritic, and antihyperalgesic agent. In addition, shown to improve defective post-receptor insulin signaling in skeletal muscle cells and enhance insulin sensitivity in rats.
Cheng, K., et al. 2013. Pharmaco. Ther.139, 334. Di Bosco, M., et al. 2008. Chem. Biol. Drug Des.71, 328. DeHaven-Hudkins, D., et al. 1999. J. Pharmacol. Exp. Ther.289, 494. Mackerer, C., et al. 1976. J. Pharmacol. Exp. Ther.199, 131.
Wear suitable protective clothing, gloves and eye/face protection. If swallowed, seek medical advice immediately and show this container or label.
Product Usage Statements
Storage and Shipping Information
Ship Code
Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity
Toxic
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
+2°C to +8°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number
GTIN
5.08162.0001
04055977261738
Documentation
Loperamide Hydrochloride - CAS 34552-83-5 - Calbiochem MSDS
Loperamide Hydrochloride - CAS 34552-83-5 - Calbiochem Certificates of Analysis
Title
Lot Number
508162
References
Reference overview
Cheng, K., et al. 2013. Pharmaco. Ther.139, 334. Di Bosco, M., et al. 2008. Chem. Biol. Drug Des.71, 328. DeHaven-Hudkins, D., et al. 1999. J. Pharmacol. Exp. Ther.289, 494. Mackerer, C., et al. 1976. J. Pharmacol. Exp. Ther.199, 131.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
A very potent and highly selective peripheral resctricted µ-opioid receptor agonist (Ki = 2 nM). Often used as an antidiarrheal, antipruritic, and antihyperalgesic agent. In addition, shown to improve defective post-receptor insulin signaling in skeletal muscle cells and enhance insulin sensitivity in rats.
Form
White solid
CAS number
34552-83-5
Chemical formula
C₂₉H₃₃ClN₂O₂·HCl
Structure formula
Purity
≥99% by HPLC
Solubility
DMSO (50 mM) or Ethanol (50 mM). Warming is required for complete solubilization in ethanol.
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Toxic
References
Cheng, K., et al. 2013. Pharmaco. Ther.139, 334. Di Bosco, M., et al. 2008. Chem. Biol. Drug Des.71, 328. DeHaven-Hudkins, D., et al. 1999. J. Pharmacol. Exp. Ther.289, 494. Mackerer, C., et al. 1976. J. Pharmacol. Exp. Ther.199, 131.
