189826 Sigma-AldrichInSolution™ 5-Aza-2ʹ-Deoxycytidine - CAS 2353-33-5 - Calbiochem
A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligan
More>> A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines. Less<<Synonyms: Decitabine
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Overview
Key Spec Table
CAS # | Empirical Formula |
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2353-33-5 | C₈H₁₂N₄O₄ |
Pricing & Availability
Catalogue Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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189826-10MG |
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Glass bottle | 10 mg |
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Description | |
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Overview | A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines. Also enhances apoptosis induced by HDAC (Histone Deacetylase) inhibitors. The solid form of this compound (Cat. No. 189825) is also available. |
Catalogue Number | 189826 |
Brand Family | Calbiochem® |
Synonyms | Decitabine |
Product Information | |
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CAS number | 2353-33-5 |
Form | Liquid |
Formulation | A 100 mM (10 mg/438 µl) solution of 5-Aza-2ʹ-Deoxycytidine (Cat. No. 189825) in DMSO. |
Hill Formula | C₈H₁₂N₄O₄ |
Chemical formula | C₈H₁₂N₄O₄ |
Hygroscopic | Hygroscopic |
Structure formula Image | |
Quality Level | MQ100 |
Biological Information | |
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Purity | ≥ 98% by HPLC |
Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Global Trade Item Number | |
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Catalogue Number | GTIN |
189826-10MG | 04055977222050 |