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362338 Glyco-SNAP-1 - Calbiochem

Glyco-SNAP-1 - Calbiochem: Malzeme Güvenlik Bilgi Formu (MSDS) veya SDS, Analiz Sertifikası (COA) ve Kalite Uygunluk Sertifikası (COQ), dosyalar, broşürler ve diğer dokümanlar.

Synonyms: N-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide

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      Overview

      Replacement Information

      Key Spec Table

      Empirical Formula
      C₁₃H₂₃N₃O₈S
      Description
      Overview

      This product has been discontinued.



      A water-soluble nitric oxide (NO) donor. More stable (t½ = 28.5-30.2 hr) than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8 - 9). The SNAP moiety acts as an NO group donor and the sugar moiety provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes at a much slower rate in the presence of thiols such as cysteine or glutathione.
      Catalogue Number362338
      Brand Family Calbiochem®
      SynonymsN-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide
      References
      ReferencesHou, Y., et al. 1999. Methods Enzymol. 301, 242.
      Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett. 6, 2575.
      Product Information
      ATP CompetitiveN
      FormGreen crystalline solid
      Hill FormulaC₁₃H₂₃N₃O₈S
      Chemical formulaC₁₃H₂₃N₃O₈S
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetA water-soluble nitric oxide (NO) donor
      Purity≥96% by NMR
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      362338 0

      Documentation

      Glyco-SNAP-1 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      Glyco-SNAP-1 - Calbiochem Certificates of Analysis

      TitleLot Number
      362338

      References

      Reference overview
      Hou, Y., et al. 1999. Methods Enzymol. 301, 242.
      Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett. 6, 2575.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-July-2008 RFH
      SynonymsN-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide
      DescriptionA water-soluble and stable nitric oxide (NO) donor (t½ = 28.5-30.2 hr). Glyco-SNAP-1 is more stable than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8-9). The SNAP moiety acts as an NO group donor and the sugar fragment provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes much more slowly in the presence of thiols such as cysteine or glutathione.
      FormGreen crystalline solid
      Chemical formulaC₁₃H₂₃N₃O₈S
      Structure formulaStructure formula
      Purity≥96% by NMR
      SolubilityH₂O (100 mg/ml), Aqueous Buffers (100 mg/ml), Methanol (5 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Toxicity Standard Handling
      ReferencesHou, Y., et al. 1999. Methods Enzymol. 301, 242.
      Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett. 6, 2575.