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345744 Ganglioside GT1b, Trisialo, Triammonium Salt, Bovine Brain - Calbiochem

Overview

Key Spec Table

Empirical Formula
C₉₅H₁₆₂N₅O₄₇ · 3NH₄

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345744-1MG
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      Description
      OverviewInhibits Con A-stimulated mitogenesis in murine T cells. Lymphocyte marker in cancer patients. Readily converted to GD1b-disialoganglioside by bacterial and other mammalian neuraminidases without detergent or bile salts.
      M.W. 2180.5 (based on stearoyl - 18:0).
      Catalogue Number345744
      Brand Family Calbiochem®
      SynonymsNeu5Acα2,3Galβ1,3GalNAcβ1,4(Neu5Acα2,8Neu5Acα2,3)Galβ1,4Glcβ1,1 Ceramide, 3NH₄
      References
      ReferencesHakomori, S. 1985. Cancer Res. 45, 2405.
      Momoi, T., et al. 1976. Biochim. Biophys. Acta 441, 488.
      Warren, L. 1959. J. Biol. Chem. 234, 1971.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      Hill FormulaC₉₅H₁₆₂N₅O₄₇ · 3NH₄
      Chemical formulaC₉₅H₁₆₂N₅O₄₇ · 3NH₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetInhibits Con A-stimulated mitogenesis in murine T cells
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableN
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator(4°C). Stock solutions are stable for up to 6 months at 4°C.
      Global Trade Item Number
      Catalogue Number GTIN
      345744-1MG 04055977193862