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AB3383-I Anti-UTF1 Antibody

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AB3383-I
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB3383-I
      ReplacesAB3383
      DescriptionAnti-UTF1 Antibody
      Alternate Names
      • UTF1
      • Undifferentiated embryonic cell transcription factor 1
      Background InformationUndifferentiated embryonic cell transcription factor 1 is a nucleus protein encoded by the UTF1 gene in human and functions as a transcriptional coactivator of ATF2. UTF1 is reported to interact with the ATF-2 metal binding motif via the leucine zipper motif within its conserved domain 2 (CD2) and both CD1 & CD2 of UTF1 and also independently mediates association with TATA-binding protein-containing complex. (PMID 9749258)
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-UTF1 Antibody is an antibody against UTF1 for use in Western Blotting and Immunohistochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected UTF1 in mouse kidney and rat liver tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human UTF1 near N-terminus.
      EpitopeNear N-terminus
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Mouse
      • Rat
      Species Reactivity NoteMouse, Rat. Predicted to react with Human based on 100% sequence homology. Other homologies: mouse, rat 95%.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • UTF1
      Purification MethodAffinity
      UniProt Number
      Molecular Weight~48 kDa observed. UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells (Okuda, A., et al. (1998). EMBO. 17(7):2019–2032).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse embryonic stem cell lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected UTF1 in 10 µg of mouse embryonic stem cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB3383-I 04055977145014

      Documentation

      Anti-UTF1 Antibody MSDS

      Title

      Safety Data Sheet (SDS) 

      Anti-UTF1 Antibody Certificates of Analysis

      TitleLot Number
      Anti-UTF1 - 3255322 3255322
      Anti-UTF1 - 3772216 3772216
      Anti-UTF1 -Q2524835 Q2524835

      References

      Reference overviewPub Med ID
      UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells.
      Okuda, A; Fukushima, A; Nishimoto, M; Orimo, A; Yamagishi, T; Nabeshima, Y; Kuro-o, M; Nabeshima, Yi; Boon, K; Keaveney, M; Stunnenberg, HG; Muramatsu, M
      The EMBO journal  17  2019-32  1998

      Show Abstract
      9524124 9524124

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      Technical Info

      Title
      White Paper: Further considerations of antibody validation and usage.

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies