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Merck

569391

Anti-Stathmin Rabbit pAb

liquid, Calbiochem®

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UNSPSC Code:
12352203

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Product Name

Anti-Stathmin Rabbit pAb, liquid, Calbiochem®

biological source

rabbit

antibody product type

primary antibodies

clone

polyclonal

form

liquid

does not contain

preservative

species reactivity (predicted by homology)

mammals

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

Quality Level

100

Application

Immunoblotting (1:20,000)

Immunohistochemistry (1:1000)

Immunoprecipitation (see comments)

Disclaimer

Toxicity: Standard Handling (A)

General description

This product has been discontinued.



Recognizes the ~17 kDa stathmin protein.

Rabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~17 kDa stathmin protein.

Immunogen

a synthetic peptide corresponding to amino acids near the C-terminus of mammalian stathmin

Other Notes

Does not cross-react with other cellular proteins as determined by immunoblotting. For immunoprecipitation, 1 µl of undiluted serum will immunoprecipitate approximately 20 ng of stathmin. Variables associated with assay conditions will dictate the proper working dilutions.
Koppel, J., et al. 1990. J. Biol. Chem.265, 3703.

Physical form

Undiluted serum.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10-13 - German Storage Class 10 to 13

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sangyan Chen et al.
Oncology reports, 41(3), 2051-2059 (2019-01-11)
Our previous studies demonstrated that high expression of oncoprotein 18 (Op18)/stathmin promotes malignant transformation of non‑small cell lung cancer NCI‑H1299 cells. Investigation of the cellular settings determined that NCI‑H1299 cells were genetically p53 deficient. In order to determine whether p53
Yan Zhao et al.
Oncology reports, 41(1), 501-511 (2018-10-16)
Our previous studies have identified that silencing oncoprotein 18 (Op18)/stathmin via RNA interference (RNAi) inhibited autocrine interleukin‑10 (IL‑10) and enhanced the sensitivity to Taxol in NCI‑H1299 non‑small cell lung cancer cells. In this study, whether autocrine IL‑10 regulates Op18/stathmin signaling in
Noriaki Ohkawa et al.
Journal of cell science, 120(Pt 8), 1447-1456 (2007-03-29)
The regulation of microtubule dynamics is important for the appropriate arborization of neuronal dendrites during development, which in turn is critical for the formation of functional neural networks. Here we show that stathmin, a microtubule destabilizing factor, is downregulated at
Chien-Lun Chen et al.
Molecular & cellular proteomics : MCP, 14(9), 2466-2478 (2015-06-18)
More than 380,000 new cases of bladder cancer are diagnosed worldwide, accounting for ∼150,200 deaths each year. To discover potential biomarkers of bladder cancer, we employed a strategy combining laser microdissection, isobaric tags for relative and absolute quantitation labeling, and
Yi-Hsin Tseng et al.
Scientific reports, 6, 38756-38756 (2016-12-10)
Stathmin (STMN1), a recognized oncoprotein upregulated in various solid tumors, promotes microtubule disassembly and modulates tumor growth and migration activity. However, the mechanisms underlying the genetic regulation of STMN1 have yet to be elucidated. In the current study, we report
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