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MABT106 Anti-Protein Spindly Antibody, clone 9D10.2

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MABT106
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, HICC, WBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABT106
      DescriptionAnti-Protein Spindly Antibody, clone 9D10.2
      Alternate Names
      • Protein Spindly
      • hSpindly
      • Arsenite-related gene 1 protein
      • Coiled-coil domain-containing protein 99
      • Rhabdomyosarcoma antigen MU-RMS-40.4A
      Background InformationProtein spindly, otherwise known as the coiled-coil domain-containing protein 99 (CCDC99), is a phosphoprotein that regulates mitosis. It interacts with the Rod/ZW10/Zwilch complex, and is involved in recruiting, docking, and alignment of motor protein dynein at mitotic kinetochores. Spindly may also be involved in checkpoint signaling and microtubule attachment.
      References
      Product Information
      FormatPurified
      Control
      • HEK293 cell lysate
      PresentationPurified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Protein Spindly using this Anti-Protein Spindly Antibody, clone 9D10.2 validated for use in ICC, Western Blotting.
      Key Applications
      • Immunocytochemistry
      • Western Blotting
      Application NotesImmunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Protein Spindly in HeLa and NIH/3T3.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Protein Spindly.
      Clone9D10.2
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgMκ
      Species Reactivity
      • Mouse
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CCDC99
      UniProt Number
      Molecular Weight~70 kDa observed. This protein is known to exist in two isoforms at 70 kDa and 56 kDa. An uncharacterized band may be observed at ~38 kDa in some cell lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in HEK293 cell lysate.

      Western Blot Analysis: 0.1 µg/mL of this antibody detected Protein Spindly in 10 µg of HEK293 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABT106 04053252551130

      Documentation

      Anti-Protein Spindly Antibody, clone 9D10.2 MSDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Protein Spindly Antibody, clone 9D10.2 Certificates of Analysis

      TitleLot Number
      Anti-Protein Spindly, clone 9D10.2 - 3948900 3948900
      Anti-Protein Spindly, clone 9D10.2 - Q2050293 Q2050293
      Anti-Protein Spindly, clone 9D10.2 -2771827 2771827
      Anti-Protein Spindly, clone 9D10.2 Monoclonal Antibody 2993680
      Anti-Protein Spindly, clone 9D10.2, Monoclonal Antibody 2833490
      Anti-Protein Spindly, clone 9D10.2_2825460 2825460

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies