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ABT253 Anti-Periostin Antibody (C-term)

Anti-Periostin Antibody (C-term) is an antibody against Periostin (C-term) for use in western blotting.

Anti-Periostin Antibody (C-term): Malzeme Güvenlik Bilgi Formu (MSDS) veya SDS, Analiz Sertifikası (COA) ve Kalite Uygunluk Sertifikası (COQ), dosyalar, broşürler ve diğer dokümanlar.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: Postn, OSF-2 UniProt Number: Q62009
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ABT253
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT253
      DescriptionAnti-Periostin Antibody (C-term)
      Alternate Names
      • Periostin
      • PN
      • Osteoblast-specific factor 2
      • OSF-2
      Background InformationPeriostin, also known as PN, or Osteoblast-specific factor 2 (OSF-2), and encoded by the gene POSTN/OSF2, is a secreted extracellular matrix protein that appears to be involved in inducing cell attachment and spreading as well as cell adhesion. In bone, Periostin enhances mineralization and assists in the incorporation of BMP1 protein into the fibronectin extracellular matrix of connective tissues. Periostin is preferentially expressed in periosteum and periodontal ligaments but can also be found expressed in developing heart and other tissues. Periostin is also over expressed in many cancers where is contributes to a growth-supportive role for such cancers and also aids in chemoresistance for cancers cells through the activation of the PI3K/Akt/surviving pathway.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Periostin Antibody (C-term) is an antibody against Periostin (C-term) for use in western blotting.
      Key Applications
      • Western Blotting
      Biological Information
      Immunogen A 188-amino acid bacterial fusion protein from the C-terminal region of mouse periostin.
      EpitopeC-terminus
      Concentration1 mg/mL
      HostRabbit
      SpecificityThis antibody detects a subset of splice variants of Periostin.
      Species Reactivity
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Postn
      • OSF-2
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~80-85 kDa observed. Multiple splice variants detected.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse lung tissue lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected Periostin in 10 µg of mouse lung tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABT253 04053252976865

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies