Millipore Sigma Vibrant Logo

05-346 Anti-MAP2 Antibody, clone 5F9

View Products on Sigmaaldrich.com
05-346
200 µg  
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited Availability
Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Special Offers

       

      Contact Customer Service

      Overview

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R, RbWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue Number05-346
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-MAP2 Antibody, clone 5F9
      Product Information
      FormatPurified
      Presentation200 µg of protein G purified mouse IgG1 in 200 µL of storage buffer (0.02 M phosphate buffer, pH 7.6, 0.25 M NaCl, and 0.1% sodium azide. Frozen at -20°C.
      Quality LevelMQ100
      Applications
      ApplicationDetect MAP2 using this Anti-MAP2 Antibody, clone 5F9 validated for use in WB, IH.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Biological Information
      ImmunogenPurified rat brain microtubules MAP2
      Cloneclone 5F9
      HostMouse
      SpecificityMAP2
      IsotypeIgG1
      Species Reactivity
      • Human
      • Mouse
      • Rat
      • Rabbit
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe MAP2 gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.
      Gene Symbol
      • Map2
      • Mtap2
      Purification MethodProtein G Chromatography
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P15146 # MAP2 is a neuron-specific protein that stabilizes microtubules in the dendrites of postmitotic neurons. Its major fucnction is to stabilize neuronal shape by promoting microtubule synthesis and cross-linking with other components of the cytoskelton.
      SIZE: 1,861 amino acids (Isofoim 1); 1830 amino acids (Isofoim 2); 467 amino acids (Isofoim 3); 498 amino acids (Isofoim 4)
      SUBCELLULAR LOCATION: Cytoplasm. Cytoskeleton.
      PTM: Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly.
      Molecular Weight202.41 kDa
      Product Usage Statements
      Quality Assuranceroutinely evaluated on rat brain microsomal preparation (Catalog #12-144).
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size200 µg
      Global Trade Item Number
      Catalogue Number GTIN
      05-346 04053252404795