Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together: -MAPmates™ that require a different assay buffer -Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9) -PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701) -More than 1 phospho-MAPmate™ for a single target (Akt, STAT3) -GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
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Select A Species, Panel Type, Kit or Sample Type
To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
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96-Well Plate
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Add Additional Reagents (Buffer and Detection Kit is required for use with MAPmates)
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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A Tale of Two Laboratories Validated antibodies for cutting-edge research
What’s the difference between histidine and phosphohistidine?
If you took chemistry, you may know that the difference is just a handful of atoms. That difference can determine the state of a whole organism. But without the right tools, researchers cannot discover the biological function of this chemical difference.
Decades ago, researchers at our Southern California laboratories realized the importance of developing precision reagents, called antibodies, to enable life scientists to distinguish these subtle chemical differences in signaling molecules. Antibodies are molecular recognition proteins that carry out immune functions in our bodies.
At Merck, antibodies are produced from lab animals and are tested using a stringent validation process. Much of the biological research conducted today relies on commercially available antibodies, including those developed by us, for protein detection, purification, and quantification.
(Photo of Salk Institute by TheNose)
Laboratory 2: San Diego, California
About 50 miles away, at the Salk Institute for Biological Studies, Dr. Tony Hunter and his team developed a new way to track some of the most elusive proteins in the body—in particular, the unstable phosphohistidine. When they began the study, no antibodies existed that could specifically detect phosphohistidine, so they developed the antibodies themselves.
Today, the Hunter lab’s antibodies are poised to unlock the field of phosphohistidine signaling research. We have licensed the antibodies to help labs around the world use this technology. Detect pHis now!
Validated antibodies, 100 percent guaranteed.
This story illustrates how we identify the most relevant antibodies for current research. We constantly review, assess, and determine which antibodies are the most suitable for research today and make them commercially available. We’ve centered our validation processes on the principle that a thoroughly tested antibody has more value to our customers, and so we provide a 100-percent guarantee that our antibodies will perform according to our specifications.
