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Buffer Detection Kit for Magnetic Beads
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554325
Sigma-AldrichResveratrol - CAS 501-36-0 - Calbiochem
A phenolic product found in both grape skins and wines.
More>>A phenolic product found in both grape skins and wines. Less<<
Resveratrol - CAS 501-36-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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Description
Overview
A phenolic product found in both grape skins and wines. Has antifungal, antitumor, and antioxidative properties. A specific inhibitor of cyclooxygenase-1 (COX-1; ED50 = 15 µM). Also inhibits the hydroxyperoxidase activity of COX-1 (ED50 = 3.7 µM). Strongly inhibits insoluble transthyretin (TTR) amyloid fibril formation. Inhibits phorbol ester-induced free radical formation in HL-60 cells (ED50 = 27 µM) and acts as an anti-mutagenic agent (ED50 = 15 µM) in TM677 cells treated with DMBA. Also a selective inhibitor of P450 1A1. Reported to activate sirtuins and promote the survival of eukaryotic cells.
Catalogue Number
554325
Brand Family
Calbiochem®
Synonyms
trans-3,4ʹ,5-Trihydroxystilbene
References
References
Howitz, K.T., et al. 2003. Nature425, 191. Lin, H.Y., et al. 2002. J. Urol.168, 748. Klabunde, T., et al. 2000. Nat. Struct. Biol.7, 312. Chun, Y.J., et al. 1999. Biochem. Biophys. Res. Commun.262, 20. Jang, M., et al. 1997. Science 275, 218. Chen, C.K., et al. 1996. Gen. Pharmacol.27, 363.
Resveratrol - CAS 501-36-0 - Calbiochem Certificates of Analysis
Title
Lot Number
554325
References
Reference overview
Howitz, K.T., et al. 2003. Nature425, 191. Lin, H.Y., et al. 2002. J. Urol.168, 748. Klabunde, T., et al. 2000. Nat. Struct. Biol.7, 312. Chun, Y.J., et al. 1999. Biochem. Biophys. Res. Commun.262, 20. Jang, M., et al. 1997. Science 275, 218. Chen, C.K., et al. 1996. Gen. Pharmacol.27, 363.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
17-December-2018 JSW
Synonyms
trans-3,4ʹ,5-Trihydroxystilbene
Description
A phenolic product found in both grape skin and wines. Has anti-fungal, anti-tumor and antioxidative properties. A specific inhibitor of cyclooxygenase-1 (COX-1; ED50 = 15 µM). Also inhibits the hydroxyperoxidase activity of COX-1 (ED50 = 3.7 µM). Inhibits phorbol ester-induced free radical formation in HL-60 cells (ED50 = 27 µM) and acts as an anti-mutagenic agent (ED50 = 15 µM) in TM677 cells treated with DMBA. Also selectively inhibits P450 1A1. Reported to activate sirtuins and promote the survival of eukaryotic cells.
Form
Off-white solid
CAS number
501-36-0
Chemical formula
C₁₄H₁₂O₃
Structure formula
Purity
≥98% by HPLC
Solubility
DMSO (50 mg/ml)
Storage
Protect from light +2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
Merck USA index
14, 8158
References
Howitz, K.T., et al. 2003. Nature425, 191. Lin, H.Y., et al. 2002. J. Urol.168, 748. Klabunde, T., et al. 2000. Nat. Struct. Biol.7, 312. Chun, Y.J., et al. 1999. Biochem. Biophys. Res. Commun.262, 20. Jang, M., et al. 1997. Science 275, 218. Chen, C.K., et al. 1996. Gen. Pharmacol.27, 363.
