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05-23-0701 Neurokinin A - CAS 86933-74-6 - Calbiochem

Neurokinin A - CAS 86933-74-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: NKA, Substance K, HKTDSFVGLM-NH₂, Neuromedin L

05-23-0701
  
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      Overview

      Key Spec Table

      CAS #Empirical Formula
      86933-74-6C₅₀H₈₀N₁₄O₁₄S
      Description
      OverviewPeptide belonging to the tachykinin family. A more potent bronchioconstrictor than substance P. May be released in association with the activation of polymodal C-nociceptors. May regulate neutrophil recruitment into lower respiratory tract. Exhibits higher affinity for NK-2 receptors compared to NK-1 or NK-3 and plays a role in hematopoietic regulation.
      Catalogue Number05-23-0701
      Brand Family Calbiochem®
      SynonymsNKA, Substance K, HKTDSFVGLM-NH₂, Neuromedin L
      References
      ReferencesRameshwar, P., and Gascom, P. 1996. Blood 88, 98.
      Chan, C.C., et al. 1993. Can. J. Physiol. Pharmacol. 72, 11.
      Nagahisa, A., et al. 1992. Eur. J. Pharmacol. 217, 191.
      von Essen, S.G., et al. 1992. Am. J. Physiol. 263, L226.
      Xu, X.J., and Wiesenfeld-Hallin, A. 1992. Acta Physiol. Scand. 144, 63.
      Product Information
      CAS number86933-74-6
      FormWhite to off-white solid
      FormulationSupplied as an trifluoroacetate salt.
      Hill FormulaC₅₀H₈₀N₁₄O₁₄S
      Chemical formulaC₅₀H₈₀N₁₄O₁₄S
      Hygroscopic Hygroscopic
      Sold on the basis of peptide contentY
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Peptide ContentY
      Peptide SequenceH-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH₂
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      05-23-0701 0