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400052 Hygromycin B, Streptomyces sp., Sterile-Filtered Solution in PBS, Cell Culture-Tested - CAS 31282-04-9 - Calbiochem

Hygromycin B is an aminoglycoside antibiotic that inhibits the growth of prokaryotic and eukaryotic microorganisms and mammalian cells. Inhibits protein synthesis by interfering with the translocation

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      Overview

      Key Spec Table

      CAS #Empirical Formula
      31282-04-9C₂₀H₃₇N₃O₁₃
      Description
      OverviewSterile liquid formulation of Cat. No. 400050.
      Catalogue Number400052
      Brand Family Calbiochem®
      References
      ReferencesSugimoto, K., et al. 1994. Plant J. 5, 863.
      Lee, M.G., and van der Ploeg, L.H. 1991. Gene 105, 255.
      Salauze, D., et al. 1990. Antimicrob. Agents Chemother. 34, 1915.
      Cullen, D., et al. 1987. Gene 57, 21.
      Rao, S.N., et al. 1983. Antimicrob. Agents Chemother. 24, 689.
      Santerre, R.F., et al. 1984. Gene 30, 147.
      Gonzalez, A., et al. 1978. Biochim. Biophys. Acta 521, 459.
      Product Information
      CAS number31282-04-9
      FormLiquid
      Formulation50 mg/ml active antibiotic in sterile-filtered PBS, pH 7.2.
      Hill FormulaC₂₀H₃₇N₃O₁₃
      Chemical formulaC₂₀H₃₇N₃O₁₃
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationHygromycin B is an aminoglycoside antibiotic that inhibits the growth of prokaryotic and eukaryotic microorganisms and mammalian cells. Inhibits protein synthesis by interfering with the translocation of the 70S ribosome and causes misreading of mRNA.
      Biological Information
      Biological activityPotency: ≥1000 U/mg
      Purity≥85% by HPLC and TLC
      Safety Information according to GHS
      RTECSWK2130000
      Safety Information
      R PhraseR: 26/27/28-37/38-41

      Very toxic by inhalation, in contact with skin and if swallowed.
      Irritating to respiratory system and skin.
      Risk of serious damage to eyes.
      S PhraseS: 23-26-36/37/39-45

      Do not breathe fumes.
      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic & Carcinogenic / Teratogenic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Global Trade Item Number
      Catalogue Number GTIN
      400052 0