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437694 DL-α-Lipoic Acid, Dihydro- - CAS 462-20-4 - Calbiochem

An effective antioxidant.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: DHLA, Dihydrolipoic Acid, Thiocytic Acid, Dihydro-

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437694
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
462-20-4C₈H₁₆O₂S₂

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437694-50MG
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      Description
      OverviewAn effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α1-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.
      Catalogue Number437694
      Brand Family Calbiochem®
      SynonymsDHLA, Dihydrolipoic Acid, Thiocytic Acid, Dihydro-
      References
      ReferencesPacker, L., et al. 1997. Adv. Pharmacol. 38, 79.
      Bustamante, J., et al. 1995. Free Radic. Biol. Med. 19, 339.
      Scott, B.C., et al. 1994. Free Radic. Res. 20, 119.
      Product Information
      CAS number462-20-4
      ATP CompetitiveN
      FormLight yellow liquid
      Hill FormulaC₈H₁₆O₂S₂
      Chemical formulaC₈H₁₆O₂S₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetScavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals
      Purity≥95% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      437694-50MG 04055977186857

      Documentation

      DL-α-Lipoic Acid, Dihydro- - CAS 462-20-4 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      DL-α-Lipoic Acid, Dihydro- - CAS 462-20-4 - Calbiochem Certificates of Analysis

      TitleLot Number
      437694

      References

      Reference overview
      Packer, L., et al. 1997. Adv. Pharmacol. 38, 79.
      Bustamante, J., et al. 1995. Free Radic. Biol. Med. 19, 339.
      Scott, B.C., et al. 1994. Free Radic. Res. 20, 119.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-October-2009 RFH
      SynonymsDHLA, Dihydrolipoic Acid, Thiocytic Acid, Dihydro-
      DescriptionAn effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α1-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.
      FormLight yellow liquid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number462-20-4
      Chemical formulaC₈H₁₆O₂S₂
      Structure formulaStructure formula
      Purity≥95% by TLC
      SolubilityEthanol (50 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Toxicity Irritant
      ReferencesPacker, L., et al. 1997. Adv. Pharmacol. 38, 79.
      Bustamante, J., et al. 1995. Free Radic. Biol. Med. 19, 339.
      Scott, B.C., et al. 1994. Free Radic. Res. 20, 119.