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217460 Cardiogenol C - CAS 671225-39-1 - Calbiochem

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217460
  
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      Overview

      Key Spec Table

      CAS #Empirical Formula
      671225-39-1C₁₃H₁₆N₄O₂
      Description
      Overview

      This product has been discontinued.



      A cell-permeable pyrimidine compound that potently induces the differentiation of ESCs (embryonic stem cells) into cardiomyocytes (EC50 = 100 nM) without significant cytotoxic effect even at concentrations as high as 25 µM. The induction of cardiomyogenesis by Cardiogenol C is much more efficient than that achieved by EBs (embryoid bodies) formation and DMSO treatment.

      Catalogue Number217460
      Brand Family Calbiochem®
      Synonyms2-(4-Methoxyanilino)-4-(1-hydroxyethylamino)pyrimidine
      References
      ReferencesWu, X., et al. 2004. J. Am. Chem. Soc. 126, 1590.
      Product Information
      CAS number671225-39-1
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₃H₁₆N₄O₂
      Chemical formulaC₁₃H₁₆N₄O₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetDifferentiation of ESCs (embryonic stem cells) into cardiomyocytes
      Primary Target IC<sub>50</sub>EC50 = 100 nM inducing the differentiation of ESCs (embryonic stem cells) into cardiomyocytes
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Carcinogenic / Teratogenic
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      217460 0