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508015 CTOP - CAS 103429-31-8 - Calbiochem

CTOP - CAS 103429-31-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: µ Opioid Receptor Antagonist, CTOP

Primary Target: mu opioid
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508015
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
103429-31-8C₅₀H₆₇N₁₁O₁₁S₂

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      Description
      OverviewA potent antagonist highly selective for µ opioid receptor (Ki = 0.96 nM for µ receptor and > 10,000 nM for δ receptors). Often used for studying the functional roles of µ opioid receptors in both central and peripheral nervous systems.
      Catalogue Number508015
      Brand Family Calbiochem®
      Synonymsµ Opioid Receptor Antagonist, CTOP
      References
      ReferencesFeng, Y., et al. 2012. Curr Drug Targets. 13, 230.
      Hawkins, N., et al. 1989. J. Pharmacol. Exp. Ther. 248, 73.
      Gulya, K., et al. 1988. Eur. J. Pharmacol. 150, 355.
      Product Information
      CAS number103429-31-8
      FormWhite solid
      FormulationSupplied as trifluoracetate salt
      Hill FormulaC₅₀H₆₇N₁₁O₁₁S₂
      Chemical formulaC₅₀H₆₇N₁₁O₁₁S₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetmu opioid
      Primary Target K<sub>i</sub>0.96 nM
      Purity≥95% by HPLC
      Physicochemical Information
      Peptide SequenceD-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (Orn: ornithine; Pen: penicillamine; SS bond: 2-7)
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      5.08015.0001 04055977242751

      Documentation

      CTOP - CAS 103429-31-8 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      CTOP - CAS 103429-31-8 - Calbiochem Certificates of Analysis

      TitleLot Number
      508015

      References

      Reference overview
      Feng, Y., et al. 2012. Curr Drug Targets. 13, 230.
      Hawkins, N., et al. 1989. J. Pharmacol. Exp. Ther. 248, 73.
      Gulya, K., et al. 1988. Eur. J. Pharmacol. 150, 355.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-September-2024 JSW
      Synonymsµ Opioid Receptor Antagonist, CTOP
      DescriptionA potent antagonist highly selective for µ opioid receptor (Ki = 0.96 nM for µ receptor and > 10,000 nM for δ receptors). Often used for studying the functional roles of µ opioid receptors in both central and peripheral nervous systems.
      FormWhite solid
      FormulationSupplied as trifluoracetate salt
      CAS number103429-31-8
      Chemical formulaC₅₀H₆₇N₁₁O₁₁S₂
      Peptide SequenceD-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (Orn: ornithine; Pen: penicillamine; SS bond: 2-7)
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityH₂O
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesFeng, Y., et al. 2012. Curr Drug Targets. 13, 230.
      Hawkins, N., et al. 1989. J. Pharmacol. Exp. Ther. 248, 73.
      Gulya, K., et al. 1988. Eur. J. Pharmacol. 150, 355.