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AB3420-I Anti-Surfactant Protein A Antibody

Detect SP-A using this rabbit polyclonal antibody, Anti-Surfactant Protein A Antibody validated for use in western blotting & IHC (Paraffin).

Anti-Surfactant Protein A Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: SFTPA1, COLEC4, PSAP, SFTP1, SFTPA, SFTPA1B UniProt Number: Q8IWL2
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AB3420-I
100 µg  
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      Overview

      Replacement Information

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, IH(P)RbPurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB3420-I
      ReplacesAB3420
      DescriptionAnti-Surfactant Protein A Antibody
      Alternate Names
      • Pulmonary surfactant-associated protein A1
      • PSP-A
      • PSPA
      • SP-A
      • SP-A1
      • 35 kDa pulmonary surfactant-associated protein
      • Alveolar proteinosis protein
      • Collectin-4
      Background InformationPulmonary surfactant-associated protein A1 (SP-A1, SFTPA1, PSP-A, SP-A) binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. There are four main surfactant proteins, known as SP-A, B, C, and D. SP-A was the first surfactant protein to be identified, and is also the most abundant. Its molecular mass varies from 26-38 kDa. It can be found in an open or closed form depending on the other substances present in the system. Calcium ions produce the closed-bouquet form. SP-A is necessary for the production of tubular myelin, a lipid transport structure unique to the lungs. Genetic variations in SP-A are a cause of susceptibility to pulmonary fibrosis idiopathic (IPF) and respiratory distress syndrome in premature infants (RDS).
      References
      Product Information
      FormatPurified
      Control
      • Human lung tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect SP-A using this rabbit polyclonal antibody, Anti-Surfactant Protein A Antibody validated for use in western blotting & IHC (Paraffin).
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:200 dilution from a representative lot detected Surfactant Protein A in human lung tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-type lectin domain of human Surfactant Protein A.
      EpitopeC-type lectin domain
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the C-type lectin domain of Surfactant Protein A.
      Species Reactivity
      • Human
      • Mouse
      Species Reactivity NoteDemonstrated to react with Human and Mouse. Predicted to react with Primate based on 100% sequence homology. Other homologies: Uniprot shows no homology to Rat.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SFTPA1
      • COLEC4
      • PSAP
      • SFTP1
      • SFTPA
      • SFTPA1B
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular Weight~35 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human lung tissue lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected Surfactant Protein A in 10 µg of human lung tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB3420-I 04053252904585

      Documentation

      Anti-Surfactant Protein A Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Surfactant Protein A Antibody Certificates of Analysis

      TitleLot Number
      Anti-Surfactant Protein A - 2375590 2375590
      Anti-Surfactant Protein A - 2455556 2455556
      Anti-Surfactant Protein A - 2536487 2536487
      Anti-Surfactant Protein A - 3176813 3176813
      Anti-Surfactant Protein A - 3439711 3439711
      Anti-Surfactant Protein A - 3520181 3520181
      Anti-Surfactant Protein A - 3842852 3842852
      Anti-Surfactant Protein A - 4083763 4083763
      Anti-Surfactant Protein A - 4186079 4186079
      Anti-Surfactant Protein A - Q2187159 Q2187159
      Show more

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies