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ABE1024 Anti-Oligodendrocyte transcription factor 2 (OLIG2 Antibody)

This Anti-Oligodendrocyte transcription factor 2 (OLIG2 antibody is validated for use in WB, IH(P) for the detection of Oligodendrocyte transcription factor 2 (OLIG2.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: Olig2 UniProt Number: Q9EQW6
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ABE1024
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, HWB, IH(P)GpSerumPolyclonal Antibody
      Description
      Catalogue NumberABE1024
      DescriptionAnti-Oligodendrocyte transcription factor 2 (OLIG2 Antibody)
      Alternate Names
      • Oligodendrocyte transcription factor 2
      • Oligo2
      Background InformationOligodendrocyte transcription factor 2 (OLIG2), also known as Oligodendrocyte transcription factor 2 Oligo2, Class B basic helix-loop-helix protein 1 (bHLHb1), Class E basic helix-loop-helix protein 19 (bHLHe19), Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, is encoded by the gene name OLIG2/ BHLHB1/ BHLHE19/ PRKCBP2/ RACK17. Olig2 is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. It cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Olig2 is an antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. The restricted expression of Olig2 in oligodendrocytes makes AB9610 an excellent marker of oligodendroglia and oligodendrogliomas in development and mature systems. Olig2 is expressed in the brain and oligodendrocytes. Olig2 is strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
      Product Information
      FormatSerum
      PresentationGuinea pig polyclonal serum with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Oligodendrocyte transcription factor 2 (OLIG2 antibody is validated for use in WB, IH(P) for the detection of Oligodendrocyte transcription factor 2 (OLIG2.
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Oligodendrocyte transcription factor 2 (OLIG2) in human cortical brain section tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to mouse Oligodendrocyte transcription factor 2 (OLIG2).
      EpitopeUnknown
      ConcentrationPlease refer to lot specific datasheet.
      HostGuinea Pig
      Species Reactivity
      • Mouse
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Olig2
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~37 kDa observed
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse brain tissue lysate.

      Western Blotting Analysis: A 1:1;000 dilution of this antibody detected Oligodendrocyte transcription factor 2 (OLIG2) in 10 µg of mouse brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Global Trade Item Number
      Catalogue Number GTIN
      ABE1024 04055977121551