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MAB5326A4 Anti-Nestin Antibody, clone 10C2, Alexa Fluor® 488 conjugate

Anti-Nestin Antibody, clone 10C2, Alexa Fluor 488 conjugate detects level of Nestin & has been published & validated for use in ICC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Stem Cell Research, Neuroscience Research Sub-Category: Neurofilament & Neuron Metabolism, Neuronal & Glial Markers Gene Symbol: NES, Nbla00170, FLJ21841, Nestin UniProt Number: P48681
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MAB5326A4
100 µL  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HICCMAlexaFluor®488Monoclonal Antibody
      Description
      Catalogue NumberMAB5326A4
      DescriptionAnti-Nestin Antibody, clone 10C2, Alexa Fluor® 488 conjugate
      Alternate Names
      • Nestin10c2
      • NES
      • Nbla00170
      • FLJ21841
      Background InformationNestin, a large intermediate filament protein (class Type VI) expressed during development and in myotendinous and neuromuscular junctions. Nestin expression is restricted, typically disappearing by E18. Nestin is thought to be a reasonable neuronal marker; however, recent studies have found nestin expression in other cell types such as endothelial cells {Folia Biologica, 44(5):155, 1998}. Nestin identifies the most primitive neuroepithelium but also identifies many other embryonic tissues, so it is not specific for CNS. Nestin expression is seen in almost all GBMs (Glioblastoma mulitformes) and many melanomas (both primary and metastatic) but not in any metastatic carcinoma.
      References
      Product Information
      FormatAlexaFluor®488
      Control
      • RNcell CX neural stem cells (SCC007).
      PresentationPurified mouse monoclonal IgG1 conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15mg/ml BSA.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Nestin Antibody, clone 10C2, Alexa Fluor 488 conjugate detects level of Nestin & has been published & validated for use in ICC.
      Key Applications
      • Immunocytochemistry
      Biological Information
      ImmunogenFusion protein corresponding to human Nestin.
      Clone10C2
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityThis antibody recognizes human Nestin. Antibody is not reactive with rat or mouse Nestin protein.
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • NES
      • Nbla00170
      • FLJ21841
      • Nestin
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular WeightThe uncojugated parent antibody (Catalog No. MAB5326) has an observed MW at 200-220 kDA.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunocytochemistry in human RNcell CX neural stem cells (SCC007). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected Nestin in human RNcell CX neural stem cells (SCC007).
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MAB5326A4 04053252648335

      Documentation

      Anti-Nestin Antibody, clone 10C2, Alexa Fluor® 488 conjugate SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Nestin Antibody, clone 10C2, Alexa Fluor® 488 conjugate Certificates of Analysis

      TitleLot Number
      Anti-Nestin, clone 10C2, Alexa Fluor#174; 488 conjugate - 2145967 2145967
      Anti-Nestin, clone 10C2, Alexa Fluor#174; 488 conjugate - 2271220 2271220
      Anti-Nestin, clone 10C2, Alexa Fluor#174; 488 conjugate - Q2025115 Q2025115
      Anti-Nestin, clone 10C2, Alexa Fluor® -2745909 2745909
      Anti-Nestin, clone 10C2, Alexa Fluor® 488 conjugate 3129302
      Anti-Nestin, clone 10C2, Alexa Fluor® 488 conjugate 2833530
      Anti-Nestin, clone 10C2, Alexa Fluor® 488 conjugate 2484246
      Anti-Nestin, clone 10C2, Alexa Fluor® 488 conjugate - 2290999 2290999
      Anti-Nestin, clone 10C2, Alexa Fluor® 488 conjugate - 2531561 2531561
      Anti-Nestin, clone 10C2, Alexa Fluor® 488 conjugate - 3301927 3301927
      Show more

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies