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ABN478 Anti-LFG Antibody

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ABN478
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN478
      DescriptionAnti-LFG Antibody
      Alternate Names
      • Protein lifeguard 2
      • Fas apoptotic inhibitory molecule 2
      • Neural membrane protein 35
      • Transmembrane BAX inhibitor motif-containing protein 2
      • LFG
      Background InformationProtein lifeguard 2 (LFG) is an antiapoptotic protein belonging to the BI1 family. LFG inhibits the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-death signal. LFG is expressed at high levels in the brain especially in the hippocampus. It is also highly expressed in breast cancer tissues and correlates with the grade of tumor (grade II/grade III) in primary breast tumors.
      References
      Product Information
      FormatAffinity Purified
      Control
      • EL4 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect LFG using this rabbit polyclonal antibody, Anti-LFG Antibody validated for use in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: 5 µg/mL from a representative lot detected LFG in mouse brain tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human LFG.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Mouse
      Species Reactivity NoteDemonstrated to react with Mouse. Predicted to react with Human based on immunogen design.
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • FAIM2
      • LFG
      • LFG2
      • NMP35
      • TMBIM2
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~35 kDa observed.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in EL4 cell lysate.

      Western Blotting Analysis: 1 µg/mL of this antibody detected LFG in 15 µg of EL4 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN478 04053252870453