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MABN709 Anti-DKK1, clone 2H2 Antibody

Anti-DKK1, clone 2H2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: DKK1, UNQ492/PRO1008 UniProt Number: O94907
MABN709
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABN709
      DescriptionAnti-DKK1, clone 2H2 Antibody
      Alternate Names
      • Dickkopf-related protein 1
      • Dickkopf-1
      • Dkk-1
      • hDkk-1
      • SK
      • DKK1
      Background Informationdickkopf homolog 1 (Xenopus laevis), also known as SK is a member of the dickkopf family. DKK1 is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
      References
      Product Information
      FormatAscites
      PresentationMouse monoclonal IgG2b ascitic fluid containing 0.03% sodium azide.
      Quality LevelMQ300
      Applications
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenPurified recombinant fragment of DKK1 expressed in E. Coli.
      Clone2H2
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG2b
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • DKK1
      • UNQ492/PRO1008
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~68 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Hek293 and DKK1-hIgGFc transfected HEK293 cell lysates.

      Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected DKK1 in hIgGFc transfected HEK293 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABN709 04055977172010