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Amyloid Precursor Protein Antibodies

APP is the precursor molecule whose proteolysis generates beta amyloid (Aβ), a 37 to 49 amino acid peptide that is the primary component of amyloid plaques found in Alzheimer's disease patients.

Overview

Specifications

Ordering Information

Amyloid Precursor Protein AntibodiesClear Sorting & Filtering Show Filter
Catalogue NumberDescriptionImmunogenHostKey ApplicationsSpecificitySpecies Reactivity
07-667Anti-APP Antibody synthetic peptide corresponding to amino acids 44-61 of human Amyloid Precursor Protein (APP) Rabbit Immunoprecipitation, Western Blotting APP Human, Rat, Mouse Show Pricing & Availability
AB1593Anti-Amyloid Precursor Protein Antibody, a.a. 44-63 Peptide to the N-terminal region (amino acids 44-63) of the APP protein. Goat ELISA, Immunofluorescence, Western Blotting, Immunohistochemistry, Immunohistochemistry (Paraffin) Recognizes amyloid precursor protein (APP). In Alzheimer's disease, this protein is broken down and releases the 12 amino acid b-amyloid protein that is found in senile plaques and vessels. <br /><br />The amyloid precursor protein is the subject of intensive investigations to determine how this protein is broken down abnormally in Alzheimer's disease to give rise to the b-amyloid protein which is present in senile plaques and vessels. This antiserum has been shown to be immunoreactive to the immunizing peptide by ELISA. The antiserum will immunolabel dystrophic neurites in senile plaques in both formalin-fixed paraffin sections and paraformaldehyde fixed frozen sections from Alzheimer's brain. <br /><br />This antiserum should be a valuable tool for scientist and neuropathologists who study the role of amyloid in Alzheimers's disease. Human Show Pricing & Availability
AB5300Anti-Amyloid Precursor Protein Antibody, universal APP (aa 99-126) conjugated to KLH. Rabbit Immunoprecipitation, Western Blotting Amyloid Precursor Protein (APP), Universal. Specific to amino acids 99-126. Human, Mouse, Monkey Show Pricing & Availability
AB5302Anti-Amyloid Precursor Protein Antibody, KPI Domain APP. Rabbit Immunoprecipitation, Western Blotting, Immunocytochemistry, Immunohistochemistry Amyloid Precursor Protein (APP), KPI Domain. Bovine, Human, Mouse, Monkey Show Pricing & Availability
AB5988PAnti-Amyloid Precursor Protein Antibody, Domain 770 Synthetic peptide corresponding to the OX2 domain of APP770. Rabbit Immunoprecipitation, Western Blotting, Immunocytochemistry, Immunohistochemistry Amyloid precursor protein (APP), domain 770, but not APP751 or APP695. Human, Monkey Show Pricing & Availability
FCMAB327FAnti-Alzheimer Precursor Protein A4 (NT)-FITC Antibody, clone 22C11 Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein. Mouse Flow Cytometry Antibody recognizes Alzheimer Precursor Protein Canine Show Pricing & Availability
IHCR1002-6Anti-APP A4 Antibody, a.a. 66-81 (NT), Prediluted, clone 22C11 Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein. Mouse Immunohistochemistry (Paraffin) The antibody recognizes amino acids 66-81 of the N-terminus on the pre-A4 molecule (Hilbich et al., 1993). 22C11 recognizes all three isoforms of APP, immature ~110kDa, sAPP ~120kDa, and mature ~130kDa (Hoffmann et al., 2000). The antibody is known to cross react with APLP2 (Slunt, 1994). Canine, Human, Mouse, Monkey, Pig, Rat, Fish Show Pricing & Availability
MAB343Anti-APP Antibody, APP 643-695 CT fragment, clone 2.F2.19B4 Carboxyl fragment of APP 643-695 / Jonas. Mouse Immunohistochemistry (Paraffin), Western Blotting Reacts with intact full-length Alzheimer precursor protein (APP) and selectively with the cytoplasmic carboxyl fragment of APP 643-695. Epitope has reportedly been mapped in this paper http://www.impub.co.uk/abs/W386.html Human, Rat Show Pricing & Availability
MAB348Anti-APP A4 Antibody, a.a. 66-81 of APP {NT}, clone 22C11 Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein. Mouse Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blotting Reacts with pre-A4. The antibody recognizes amino acids 66-81 of the N-terminus on the pre-A4 molecule (Hilbich et al., 1993). 22C11 recognizes all three isoforms of APP, immature ~110kDa, sAPP ~120kDa, and mature ~130kDa (Hoffmann et al., 2000). The antibody is known to cross react with APLP2 (Slunt, 1994). Canine, Human, Mouse, Monkey, Pig, Rat, Fish Show Pricing & Availability
MAB348-100ULAnti-APP A4 Antibody, a.a. 66-81 of APP (NT), clone 22C11 Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein. Mouse Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blotting Reacts with pre-A4. The antibody recognizes a N-terminal epitope on the pre-A4 molecule Human, Mouse, Rat, Monkey, Pig, Fish Show Pricing & Availability
MAB348A4Anti-Alzheimer Precursor Protein A4 Antibody, clone 22C11, Alexa Fluor® 488 conjugate Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein Mouse Immunohistochemistry, Immunocytochemistry Unconjugated MAB348 recognizes N-terminal amino acids 66-81 on the pre-A4 molecule (Hilbich et al., 1993). 22C11 recognizes all three isoforms of APP: immature, ~110kDa; sAPP, ~120kDa; and mature, ~130kDa (Hoffmann et al., 2000). This antibody is known to cross react with APLP2 (Slunt, 1994). Rat, Mouse, Human, Monkey, Pig, Canine Show Pricing & Availability
MAB348BAnti-Alzheimer Precursor Protein A4 Antibody, clone 22C11, Biotin Conj. Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein Mouse Immunohistochemistry, Immunocytochemistry This antibody recognizes Alzheimer Precursor Protein A4 at the N-temrinus. Rat, Mouse, Canine, Human, Monkey, Pig Show Pricing & Availability
MAB349Anti-Amyloid Precursor Protein Antibody, A4(695), clone 1.D5 Synthetic peptide Alz 90 [amino acids 511-608 of amyloid precursor protein pre A4(695)]. Mouse Western Blotting Reacts with the natural amyloid precursor protein A4(695). Human, Rat Show Pricing & Availability
MAB5228Anti-Amyloid Precursor Protein Antibody, Secretory, clone OM84 Amyloid Precursor Protein (APP) secreted by the EJ-1 bladder carcinoma cell line. Mouse ELISA, Western Blotting Reacts with secretory amyloid precursor protein (sAPP), but not with Amyloid-Beta protein 1-40. Human Show Pricing & Availability
MAB5354Anti-Amyloid β Precursor Protein Antibody, KPI domain, clone 4.1 Purified recombinant KPI domain of Amyloid-beta precursor protein. Mouse ELISA, Western Blotting, Immunohistochemistry Amyloid-beta Precursor Protein, KPI (Kunitz protease inhibitor) domain. The antibody reacts with both native and recombinant protein. The antibody has been shown to partially inhibit protease inhibitory properties. Human Show Pricing & Availability
MABN380Anti-APP-C99 Antibody, clone mC99(70–80) Recombinant protein corresponding to Human APP-C99. Mouse Western Blotting, Immunoprecipitation, Immunohistochemistry, Immunofluorescence Human, Mouse Show Pricing & Availability
MABN381Anti-APP-C99 Antibody, clone mC99(1-7) Recombinant protein corresponding to Human APP-C99. Mouse Western Blotting, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry Human, Mouse Show Pricing & Availability

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