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116860 Adenosine Deaminase Inhibitor, DCF - CAS 53910-25-1 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
53910-25-1C₁₁H₁₆N₄O₄

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116860-10MG
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      Glass bottle 10 mg
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      Description
      OverviewA cell-permeable purine nucleoside compound that acts as a highly potent, tight binding transition state analog inhibitor of adenosine deaminase (ADA; Ki= 2.5 pM against partially purified human erythrocytes, and 0.48 to 9.1 nM against rat liver, rat intestine, rat hepatoma and human B cells). Reported to be an immunomodulator and exert selective toxicity towards lymphocytes.
      Catalogue Number116860
      Brand Family Calbiochem®
      SynonymsPentostatin, S. antibioticus, 2ʹ-Deoxycoformycin, (8R)-3-(2-deoxy-β-D-erythro- pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
      References
      ReferencesRobak, T. 2007. Cancer Treat. Rev. 33, 710.
      Klohs, W.D. and Kraker, A.J., 1992. Pharmacol. Rev. 44, 459.
      Agarwal, R.P., et al. 1977. Biochem. Pharmacol. 26, 359.
      Product Information
      CAS number53910-25-1
      FormWhite solid
      Hill FormulaC₁₁H₁₆N₄O₄
      Chemical formulaC₁₁H₁₆N₄O₄
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Purity≥98% by HPLC
      Safety Information
      R PhraseR: 62-63

      Possible risk of impaired fertility.
      Possible risk of harm to the unborn child.
      S PhraseS: 36/37/39-45

      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Harmful & Carcinogenic / Teratogenic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      116860-10MG 04055977223934