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344300 sFRP-1 Inhibitor - CAS 915754-88-0 - Calbiochem

344300
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Overview

Key Spec Table

CAS #Empirical Formula
915754-88-0C₁₉H₂₆N₂O₄S₂

Products

Catalogue NumberPackaging Qty/Pack
344300-5MG Sklená flaša 5 mg
Description
OverviewA diphenylsulfone-sulfonamide compound that counteracts the antagonizing effect of SARP-2/sFRP-1 (secreted frizzled related protein-1) against Wnt-3/frizzled interaction and Wnt-3/frizzled-stimulated cellular functions (EC50 = 1.27 µM in a U2OS-based reporter assay) with a reported aqueous solubility of 26 µg/ml at pH 7.4 and in vitro half-lives of 12 and 26.7 min using rat and human microsomes, respectively.
Catalogue Number344300
Brand Family Calbiochem®
SynonymsN-(3-(Dimethylamino)propyl)-2-ethyl-5-(phenylsulfonyl)benzenesulfonamide, Secreted Frizzled Related Protein-1 Inhibitor, Wnt Pathway Activator IV
References
ReferencesGopalsamy, A., et al. 2008. J. Med. Chem. 51, 7670.
Product Information
CAS number915754-88-0
FormClear oil
Hill FormulaC₁₉H₂₆N₂O₄S₂
Chemical formulaC₁₉H₂₆N₂O₄S₂
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Purity≥95% by HPLC
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
344300-5MG 04055977214710