Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

524950 Vitamín B₁₂ (kyanokobalamín)

Overview

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
68-19-9200-680-0C₆₃H₈₈Co N₁₄O₁₄P1355.37 g/molPh Eur,BP,USP

Products

Catalogue NumberPackaging Qty/Pack
5249500010 Sklená flaša 10 g
5249500100 Kovová nádoba 100 g
Description
Catalogue Number524950
SynonymsCyanocobalamin
Product Information
CAS number68-19-9
EC number200-680-0
GradePh Eur,BP,USP
Hill FormulaC₆₃H₈₈Co N₁₄O₁₄P
Molar Mass1355.37 g/mol
HS Code2936 26 00
Structure formula ImageStructure formula Image
Quality LevelMQ500
Physicochemical Information
Melting Point>300 °C
pH value6 (H₂O)
Bulk density450 - 600 kg/m3
Solubility12 g/l
Safety Information according to GHS
RTECSGG3750000
Storage class10 - 13 Iné kvapaliny a tuhé látky
WGKWGK 1 mierne ohrozujúce vody
Storage and Shipping Information
StorageSkladujte pri +15°C až +25°C.
Transport Information
Declaration (railroad and road) ADR, RIDKein Gefahrgut
Declaration (transport by air) IATA-DGRNo Dangerous Good
Declaration (transport by sea) IMDG-CodeNo Dangerous Good
Specifications
Assay (photometric, calculated on dried substance)96.0 - 102.0 %
Identity (Cobalt)passes test
Identity (HPLC)passes test
Appearancedark-red, crystalline powder or dark-red crystals
Absorption ratio (A 361 nm/278 nm)1.70 - 1.90
Absorption ratio (A 361 nm/550 nm)3.15 - 3.40
Al (Aluminium)≤ 1 ppm
Fe (Iron)≤ 130 ppm
Mn (Manganese)≤ 25 ppm
Zn (Zinc)≤ 25 ppm
Related substances (HPLC, Ph Eur) (Impurity A)≤ 0.7 %
Related substances (HPLC, Ph Eur) (Impurity B)≤ 0.5 %
Related substances (HPLC, Ph Eur) (Impurity C)≤ 1.5 %
Related substances (HPLC, Ph Eur) (Impurity D)≤ 0.5 %
Related substances (HPLC, Ph Eur) (Impurity E)≤ 0.5 %
Related substances (HPLC, Ph Eur) (Impurity F)≤ 0.5 %
Related substances (HPLC, Ph Eur) (Each unspecified impurity)≤ 0.2 %
Related substances (HPLC, Ph Eur) (Sum of all impurities)≤ 3.0 %
Related substances (HPLC, USP, 7ß,8ß-Lactocyanocobalamin)≤ 1.0 %
Related substances (HPLC, USP, 50-Carboxycyanocobalamin)≤ 0.5 %
Related substances (HPLC, USP, 32-Carboxycyanocobalamin)≤ 2.0 %
Related substances (HPLC, USP, 34-Methylcyanocobalamin)≤ 1.0 %
Related substances (HPLC, USP, 8-Epi-cyanocobalamin)≤ 1.0 %
Related substances (HPLC, USP, Any other unidentified impurity)≤ 0.5 %
Related substances (HPLC, USP, Total impurities)≤ 3.0 %
Acetone (HS-GC)≤ 5000 ppm
Other residual solvents (ICH Q3C)excluded by production process
Loss on Drying (105 °C)
≤ 12.0 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur, BP, USP
≤ 12.0 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur, BP, USP
Corresponds to Ph Eur, BP, USP
Global Trade Item Number
Catalogue Number GTIN
5249500010 04022536261874
5249500100 04022536261881