Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

506135 Venlafaxine Hydrochloride - CAS 99300-78-4 - Calbiochem

506135
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
99300-78-4C₁₇H₂₇NO₂·HCl

Products

Catalogue NumberPackaging Qty/Pack
5.06135.0001 Sklená flaša 10 mg
Description
OverviewA dual reuptake inhibitor of serotonin-norepinephrine with strong preference to serotonin (Ki = 82 and 2480 nM for SERT and NET respectively). Also inhibits reuptake of dopamine. Used in studies of depression, ADHD, and stress-related anxiety.
Catalogue Number506135
Brand Family Calbiochem®
SynonymsSERT/NET Inhibitor, Venlafaxine, Serotonin-norepinephrine Inhibitor, Venlafaxien
References
ReferencesKaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci. 2, 22.
Aboelwafa, A., et al. 2010. AAPS PharmSciTech. 11, 1026.
Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry. 97, 729.
Product Information
CAS number99300-78-4
FormWhite solid
Hill FormulaC₁₇H₂₇NO₂·HCl
Chemical formulaC₁₇H₂₇NO₂·HCl
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetSERT/NET
Primary Target K<sub>i</sub>82 nM
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
5.06135.0001 04055977243130

Documentation

Venlafaxine Hydrochloride - CAS 99300-78-4 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Kaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci. 2, 22.
Aboelwafa, A., et al. 2010. AAPS PharmSciTech. 11, 1026.
Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry. 97, 729.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision15-November-2013 JSW
SynonymsSERT/NET Inhibitor, Venlafaxine, Serotonin-norepinephrine Inhibitor, Venlafaxien
DescriptionA dual reuptake inhibitor of serotonin-norepinephrine with strong preference to serotonin (Ki = 82 and 2480 nM for SERT and NET respectively). Also inhibits reuptake of dopamine. Used in studies of depression, ADHD, and stress-related anxiety.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number99300-78-4
Chemical formulaC₁₇H₂₇NO₂·HCl
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityDMSO (50 mM) or H₂O (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesKaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci. 2, 22.
Aboelwafa, A., et al. 2010. AAPS PharmSciTech. 11, 1026.
Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry. 97, 729.