Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

14-814 UbcH8 Conjugating Enzyme, 100 µg

14-814
100 µg  
Purchase on Sigma-Aldrich

Overview

Key Spec Table

Entrez Gene NumberSpeciesUni Prot Number
NM_152653.2 Human Q96LR5
Description
Catalogue Number14-814
Brand Family Upstate
Trade Name
  • Upstate
DescriptionUbcH8 Conjugating Enzyme, 100 µg
OverviewUbcH8 is a class I ubiquitin-conjugating (E2) enzyme highly similar in structure to UbcH7. UbcH8 is a primary target gene of interferon-alpha and gamma, and recent studies have indicated that UbcH8 is the E2 enzyme for the ubiquitin-like protein ISG15. These studies suggest overlap between the ISG15 and ubiquitin conjugation pathways, and have important implications for understanding the regulation and function of ISG15 in the IFN alpha/beta response. Typical enzyme concentration to support conjugation in vitro is 100nM to 1μM depending upon conditions.
Product Information
Quality LevelMQ100
Applications
ApplicationUbcH8 is a class I ubiquitin-conjugating (E2) enzyme highly similar in structure to UbcH7. UbcH8 is a primary target gene of interferon-alpha & gamma.
Biological Information
Sourceexpressed in E. coli
Entrez Gene Number
Gene Symbol
  • UBE2E2
  • FLJ25157
  • UbcH8
  • UBCH8
Purification MethodPurified using Ni2+ chelation chromatography with Ni2+ in limiting concentration.
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q96LR5 # Catalyzes the covalent attachment of ubiquitin to other proteins (Probable).
SIZE: 201 amino acids; 22255 Da
SIMILARITY: SwissProt: Q96LR5 ## Belongs to the ubiquitin-conjugating enzyme family.
Molecular Weight18 kDa
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsFor long term storage store at -80°C.
Packaging Information
Material Size100 µg
Global Trade Item Number
Catalogue Number GTIN
14-814 04053252330001