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662006 U0124 - CAS 1140528-25-1 - Calbiochem

A useful negative control for MEK inhibitors U0125 and U0126.

U0124 - CAS 1140528-25-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1,4-Diamino-2,3-dicyano-1,4-bis(methylthio)butadiene

Primary Target: MEK1
662006
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
1140528-25-1C₈H₁₀N₄S₂

Products

Catalogue NumberPackaging Qty/Pack
662006-1MG Plastová ampulka 1 mg
Description
OverviewA useful negative control for MEK inhibitors U0125 (Cat. No. 662008) and U0126 (Cat. No. 662005). Does not inhibit MEK activity even at concentrations of 100 µM.
Catalogue Number662006
Brand Family Calbiochem®
Synonyms1,4-Diamino-2,3-dicyano-1,4-bis(methylthio)butadiene
References
ReferencesFavata, M.F., et al. 1998. J. Biol. Chem. 273, 18623.
Product Information
CAS number1140528-25-1
ATP CompetitiveN
FormWhite solid
Hill FormulaC₈H₁₀N₄S₂
Chemical formulaC₈H₁₀N₄S₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMEK1
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
662006-1MG 04055977261028

Documentation

U0124 - CAS 1140528-25-1 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

U0124 - CAS 1140528-25-1 - Calbiochem Certificates of Analysis

TitleLot Number
662006

References

Reference overview
Favata, M.F., et al. 1998. J. Biol. Chem. 273, 18623.

Citations

Title
  • Neelakandan Muthukumaran, et al. (2006) Tumor necrosis factor-α differentially modulates CD44 expression in ovarian cancer cells. Molecular Cancer Research 4, 511-520.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision19-April-2011 RFH
    Synonyms1,4-Diamino-2,3-dicyano-1,4-bis(methylthio)butadiene
    DescriptionA useful negative control for the MEK inhibitors U0125 (Cat. No. 662008) and U0126 (Cat. No. 662005). Does not inhibit MEK even at concentrations of 100 µM.
    FormWhite solid
    Intert gas (Yes/No) Packaged under inert gas
    CAS number1140528-25-1
    Chemical formulaC₈H₁₀N₄S₂
    Structure formulaStructure formula
    Purity≥95% by HPLC
    SolubilityDMSO (100 mg/ml)
    Storage Protect from light
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
    Toxicity Standard Handling
    ReferencesFavata, M.F., et al. 1998. J. Biol. Chem. 273, 18623.
    Citation
  • Neelakandan Muthukumaran, et al. (2006) Tumor necrosis factor-α differentially modulates CD44 expression in ovarian cancer cells. Molecular Cancer Research 4, 511-520.
    		•