Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

616374 TRAIL, Human, Recombinant, E. coli

TRAIL, Human, Recombinant, E. coli MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Apo2L, Human, Recombinant, E. coli, TNF-Related Apoptosis-Inducing Ligand, Human, Recombinant, E. coli

616374
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
616374-100UG Plastová ampulka 100 μg
Description
OverviewRecombinant, human TRAIL (amino acids 114-281) expressed in E. coli. Ligand for TRAIL receptors DR4 and DR5. Displays potent antitumor activity against selected targets and induces apoptosis in a number of transformed cell lines, but not in normal tissues.
Catalogue Number616374
Brand Family Calbiochem®
SynonymsApo2L, Human, Recombinant, E. coli, TNF-Related Apoptosis-Inducing Ligand, Human, Recombinant, E. coli
References
ReferencesLin, Y., et al. 2000. Mol. Cell. Biol. 20, 6638.
Mitsaides, N., et al. 2000. Cancer Res. 60, 4122.
Griffith, T.S., et al. 1999. J. Exp. Med. 189, 1343.
Mariani, S.M., et al. 1997. J. Cell Biol. 137, 221.
Pan, G., et al. 1997. Science 276, 111.
Pan, G., et al. 1997. Science 277, 815.
Sheridan, J.P., et al. 1997. Science 277, 818.
Pitti, R.M., et al. 1996. J. Biol. Chem. 271, 12687.
Wiley, S.R., et al. 1995. Immunity 3, 673.
Product Information
FormLiquid
FormulationIn 500 mM NaCl, 10 mM Na₂HPO₄, 2.7 mM KCl, 2 mM KH₂PO₄, 0.1 mM DTT, ≤10% glycerol.
Quality LevelMQ100
Applications
Biological Information
Biological activityInduces apoptosis in U937 cells at 1 μg/ml within 5 h.
Purity≥95% by SDS-PAGE
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Contaminantsendotoxin <0.1 EU/µg TRAIL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze
(-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
616374-100UG 04055977186246

Documentation

TRAIL, Human, Recombinant, E. coli MSDS

Title

Safety Data Sheet (SDS) 

TRAIL, Human, Recombinant, E. coli Certificates of Analysis

TitleLot Number
616374

References

Reference overview
Lin, Y., et al. 2000. Mol. Cell. Biol. 20, 6638.
Mitsaides, N., et al. 2000. Cancer Res. 60, 4122.
Griffith, T.S., et al. 1999. J. Exp. Med. 189, 1343.
Mariani, S.M., et al. 1997. J. Cell Biol. 137, 221.
Pan, G., et al. 1997. Science 276, 111.
Pan, G., et al. 1997. Science 277, 815.
Sheridan, J.P., et al. 1997. Science 277, 818.
Pitti, R.M., et al. 1996. J. Biol. Chem. 271, 12687.
Wiley, S.R., et al. 1995. Immunity 3, 673.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2008 RFH
SynonymsApo2L, Human, Recombinant, E. coli, TNF-Related Apoptosis-Inducing Ligand, Human, Recombinant, E. coli
DescriptionRecombinant, human TRAIL (amino acids 114-281) expressed in E. coli. Ligand for TRAIL receptors DR4 and DR5. Displays potent antitumor activity against selected targets and induces apoptosis in a number of transformed cell lines, but not in normal tissues.
FormLiquid
FormulationIn 500 mM NaCl, 10 mM Na₂HPO₄, 2.7 mM KCl, 2 mM KH₂PO₄, 0.1 mM DTT, ≤10% glycerol.
Concentration Label Please refer to vial label for lot-specific concentration
Purity≥95% by SDS-PAGE
Contaminantsendotoxin <0.1 EU/µg TRAIL
Biological activityInduces apoptosis in U937 cells at 1 μg/ml within 5 h.
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze
(-70°C).
Toxicity Standard Handling
ReferencesLin, Y., et al. 2000. Mol. Cell. Biol. 20, 6638.
Mitsaides, N., et al. 2000. Cancer Res. 60, 4122.
Griffith, T.S., et al. 1999. J. Exp. Med. 189, 1343.
Mariani, S.M., et al. 1997. J. Cell Biol. 137, 221.
Pan, G., et al. 1997. Science 276, 111.
Pan, G., et al. 1997. Science 277, 815.
Sheridan, J.P., et al. 1997. Science 277, 818.
Pitti, R.M., et al. 1996. J. Biol. Chem. 271, 12687.
Wiley, S.R., et al. 1995. Immunity 3, 673.