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GF176 TGF-β-III Protein, Human Recombinant

TGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily.

TGF-β-III Protein, Human Recombinant MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P10600 Entrez Gene Number: 7043
GF176
10µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

SourcePurity
E. coli.Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses.
Description
Catalogue NumberGF176
DescriptionTGF-β-III Protein, Human Recombinant
Alternate Names
  • Transforming Growth Factor Beta 3
  • TGF-Beta-3
  • TGF-Beta-III
Background InformationTGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily. TGF-β-I, TGF-β-II and TGF-β-III are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial mesenchymal transition. TGF-β3 regulates molecules involved in cellular adhesion and extracellular matrix formation during the process of palate development. TGF-β3 also plays an essential role in controlling the development of lungs in mammals and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. Recombinant TGF-β-III is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
References
Product Information
PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
ApplicationTGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily.
Biological Information
PurityProduct is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses.
SourceE. coli.
Entrez Gene Number
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceDetermined by TGF-β-III’s ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size10µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
GF176 04053252599675

Documentation

TGF-β-III Protein, Human Recombinant MSDS

Title

Safety Data Sheet (SDS) 

TGF-β-III Protein, Human Recombinant Certificates of Analysis

TitleLot Number
Recombinant Human TGF-#946;-III - Q2048992 Q2048992
Recombinant Human -2579928 2579928
Recombinant Human -2729464 2729464
Recombinant Human -2732282 2732282
Recombinant Human TGF--III - 2298445 2298445
Recombinant Human TGF-β-III - 3326100 3326100
Recombinant Human TGF-β-III - 3403265 3403265
Recombinant Human TGF-β-III - 3504398 3504398
Recombinant Human TGF-β-III - 3530663 3530663
Recombinant Human TGF-β-III - 3587170 3587170
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Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors