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567703 Spermine NONOate - CAS 136587-13-8 - Calbiochem

Complex of nitric oxide (NO) with spermine.

Spermine NONOate - CAS 136587-13-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: N-(2-Aminoethyl)-N-(2-hydroxy-2-nitrosohydrazino)-1,2-ethylenediamine, NOC-22

567703
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
136587-13-8C₁₀H₂₆N₆O₂
Description
OverviewComplex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t½)in PBS, pH 7.4 is 230 minutes at 22°C. Relatively stable in alkaline solution (≥pH 10.0).
Catalogue Number567703
Brand Family Calbiochem®
SynonymsN-(2-Aminoethyl)-N-(2-hydroxy-2-nitrosohydrazino)-1,2-ethylenediamine, NOC-22
References
ReferencesRamamurthi, A. and Lewis, R.S. 1997. Chem. Res. Toxicol. 10, 408.
Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.
Maragos, C.M., et al. 1993. Cancer Res. 53, 564.
Wink, D.A., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9813.
Maragos, C.M., et al. 1991. J. Med. Chem. 34, 3242.
Product Information
CAS number136587-13-8
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₀H₂₆N₆O₂
Chemical formulaC₁₀H₂₆N₆O₂
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetConvenient reagent for preparing aqueous solutions of NO
Purity≥98% by UV
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O just prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
567703 0

Documentation

Spermine NONOate - CAS 136587-13-8 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Spermine NONOate - CAS 136587-13-8 - Calbiochem Certificates of Analysis

TitleLot Number
567703

References

Reference overview
Ramamurthi, A. and Lewis, R.S. 1997. Chem. Res. Toxicol. 10, 408.
Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.
Maragos, C.M., et al. 1993. Cancer Res. 53, 564.
Wink, D.A., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9813.
Maragos, C.M., et al. 1991. J. Med. Chem. 34, 3242.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision11-September-2008 RFH
SynonymsN-(2-Aminoethyl)-N-(2-hydroxy-2-nitrosohydrazino)-1,2-ethylenediamine, NOC-22
DescriptionComplex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t½) of NO release = 230 min (PBS, pH 7.4, 22°C).
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number136587-13-8
Chemical formulaC₁₀H₂₆N₆O₂
Structure formulaStructure formula
Purity≥98% by UV
SolubilityH₂O or 0.1 N NaOH (≥pH 10)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O just prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesRamamurthi, A. and Lewis, R.S. 1997. Chem. Res. Toxicol. 10, 408.
Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.
Maragos, C.M., et al. 1993. Cancer Res. 53, 564.
Wink, D.A., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9813.
Maragos, C.M., et al. 1991. J. Med. Chem. 34, 3242.