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506188 Sertraline Hydrochloride - CAS 79559-97-0 - Calbiochem

Sertraline Hydrochloride - CAS 79559-97-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Serotonin (5-HT) Reuptake Inhibitor, Sertraline, Zoloft

Primary Target: 5-HT uptake transporter
506188
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
79559-97-0C₁₇H₁₇Cl₂N•HCl

Products

Catalogue NumberPackaging Qty/Pack
5.06188.0001 Sklená flaša 10 mg
Description
OverviewA very potent uptake inhibitor highly selective for serotonin (Ki = 3.3 nM). Clinically prescribed as an antidepressant drug. Often used in studying major depressive disorders.
Catalogue Number506188
Brand Family Calbiochem®
SynonymsSerotonin (5-HT) Reuptake Inhibitor, Sertraline, Zoloft
References
ReferencesBrunoni, R., et al. 2013. JAMA Psychiatry. 70, 383.
Kobayashi, K., et al. 1995. Br. J. Clin. Pharmacol. 40, 481.
Heym, J., et al. 1988. J. Clin. Psychiatry. 49 Suppl, 40.
Koe, K., et al. 1983. J. Pharmacol. Exp. Ther. 226, 700.
Product Information
CAS number79559-97-0
FormWhite solid
Hill FormulaC₁₇H₁₇Cl₂N•HCl
Chemical formulaC₁₇H₁₇Cl₂N•HCl
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Target5-HT uptake transporter
Primary Target K<sub>i</sub>3.3 nM
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
5.06188.0001 04055977243147

Documentation

Sertraline Hydrochloride - CAS 79559-97-0 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Brunoni, R., et al. 2013. JAMA Psychiatry. 70, 383.
Kobayashi, K., et al. 1995. Br. J. Clin. Pharmacol. 40, 481.
Heym, J., et al. 1988. J. Clin. Psychiatry. 49 Suppl, 40.
Koe, K., et al. 1983. J. Pharmacol. Exp. Ther. 226, 700.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision15-November-2013 JSW
SynonymsSerotonin (5-HT) Reuptake Inhibitor, Sertraline, Zoloft
DescriptionA very potent uptake inhibitor highly selective for serotonin (Ki = 3.3 nM). Clinically prescribed as an antidepressant drug. Often used in studying major depressive disorders.
FormWhite solid
CAS number79559-97-0
Chemical formulaC₁₇H₁₇Cl₂N•HCl
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityDMSO (100 mM) or Ethanol (50 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesBrunoni, R., et al. 2013. JAMA Psychiatry. 70, 383.
Kobayashi, K., et al. 1995. Br. J. Clin. Pharmacol. 40, 481.
Heym, J., et al. 1988. J. Clin. Psychiatry. 49 Suppl, 40.
Koe, K., et al. 1983. J. Pharmacol. Exp. Ther. 226, 700.