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565625 SC-68376 - CAS 318480-82-9 - Calbiochem

SC-68376 - CAS 318480-82-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-Methyl-4-phenyl-5-(4-pyridyl)oxazole

Primary Target: p38MAPK
565625
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
318480-82-9C₁₅H₁₂N₂O
Description
Overview

This product has been discontinued.



A potent, reversible, cell-permeable, ATP-competitive, and selective inhibitor of p38 MAP kinase activity in a dose-dependent manner (IC50 = 2-5 µM). Does not inhibit basal ERK or IL-1-induced JNK activity.
Catalogue Number565625
Brand Family Calbiochem®
Synonyms2-Methyl-4-phenyl-5-(4-pyridyl)oxazole
References
ReferencesGuan, Z., et al. 1998. J. Biol. Chem. 273, 12901.
Guan, Z., et al. 1997. J. Biol. Chem. 272, 8083.
Product Information
CAS number318480-82-9
ATP CompetitiveY
FormWhite to yellow semi-solid
Hill FormulaC₁₅H₁₂N₂O
Chemical formulaC₁₅H₁₂N₂O
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetp38MAPK
Primary Target IC<sub>50</sub>2-5 µM against p38MAP kinase activity
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
565625 0

Documentation

SC-68376 - CAS 318480-82-9 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

SC-68376 - CAS 318480-82-9 - Calbiochem Certificates of Analysis

TitleLot Number
565625

References

Reference overview
Guan, Z., et al. 1998. J. Biol. Chem. 273, 12901.
Guan, Z., et al. 1997. J. Biol. Chem. 272, 8083.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-January-2010 RFH
Synonyms2-Methyl-4-phenyl-5-(4-pyridyl)oxazole
DescriptionPotently, reversible, cell-permeable, ATP-competitive and selectively inhibits p38 mitogen-activated protein kinase (MAPK) activity in a dose-dependent manner (IC50 = 2-5 µM). Does not inhibit basal ERK or IL-1-induced JNK activity.
FormWhite to yellow semi-solid
CAS number318480-82-9
Chemical formulaC₁₅H₁₂N₂O
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (200 mg/ml)
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Standard Handling
ReferencesGuan, Z., et al. 1998. J. Biol. Chem. 273, 12901.
Guan, Z., et al. 1997. J. Biol. Chem. 272, 8083.