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559395 SB 203580, Hydrochloride - CAS 869185-85-3 - Calbiochem

559395
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Overview

Key Spec Table

CAS #Empirical Formula
869185-85-3C₂₁H₁₆FN₃OS · HCl

Products

Catalogue NumberPackaging Qty/Pack
559395-10MG Plastová ampulka 10 mg
559395-1MG Plastová ampulka 1 mg
Description
OverviewA water-soluble form of the potent MAP kinase inhibitor SB 203580 (Cat. No. 559389).
Catalogue Number559395
Brand Family Calbiochem®
Synonyms4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole, HCl, p38 MAP Kinase Inhibitor XVI, Hydrochloride
Product Information
CAS number869185-85-3
ATP CompetitiveN
FormBright yellow solid
Hill FormulaC₂₁H₁₆FN₃OS · HCl
Chemical formulaC₂₁H₁₆FN₃OS · HCl
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary Targetp38 MAP kinase
Primary Target IC<sub>50</sub>34 nM against p38 MAP kinase in vitro, 600 nM in cells; 50-100 nM against IL-1 and TNF-a production from LPS-stimulated human monocytes and the human monocyte cell line THP-1; 0.2-1.0 µM against platelet aggregation caused by collagen
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
559395-10MG 04055977192575
559395-1MG 04055977192568