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559387 SB 202474 - CAS 172747-50-1 - Calbiochem

SB 202474 - CAS 172747-50-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 4-Ethyl-2(p-methoxyphenyl)-5-(4ʹ-pyridyl)-IH-imidazole

Primary Target: p38β
559387
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
172747-50-1C₁₇H₁₇N₃O
Description
Overview

This product has been discontinued.



A negative control for SB202190 (Cat. No. 559388) and SB203580 (Cat. No. 559389) in p38 MAP kinase inhibition studies.
Catalogue Number559387
Brand Family Calbiochem®
Synonyms4-Ethyl-2(p-methoxyphenyl)-5-(4ʹ-pyridyl)-IH-imidazole
References
ReferencesNath, R., et al. 2001. Cell Mol. Biol. Lett. 6, 173.
Yu, R., et al. 2000. J. Biol. Chem. 275, 2322.
Lee, J.C., et al. 1994. Nature 372, 739.
Product Information
CAS number172747-50-1
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₁₇H₁₇N₃O
Chemical formulaC₁₇H₁₇N₃O
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetp38β
Primary Target IC<sub>50</sub>34 nM
Purity≥97% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
559387 0

Documentation

SB 202474 - CAS 172747-50-1 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

SB 202474 - CAS 172747-50-1 - Calbiochem Certificates of Analysis

TitleLot Number
559387

References

Reference overview
Nath, R., et al. 2001. Cell Mol. Biol. Lett. 6, 173.
Yu, R., et al. 2000. J. Biol. Chem. 275, 2322.
Lee, J.C., et al. 1994. Nature 372, 739.

Citations

Title
  • Ralf Gutzmer, et al. (2005) Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells. Journal of Immunology 5224-5232.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision19-April-2011 RFH
    Synonyms4-Ethyl-2(p-methoxyphenyl)-5-(4ʹ-pyridyl)-IH-imidazole
    DescriptionA negative control for MAP kinase inhibition studies.
    FormOff-white solid
    CAS number172747-50-1
    Chemical formulaC₁₇H₁₇N₃O
    Structure formulaStructure formula
    Purity≥97% by HPLC
    SolubilityDMSO (25 mg/ml) or methanol
    Storage Protect from light
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    Toxicity Standard Handling
    ReferencesNath, R., et al. 2001. Cell Mol. Biol. Lett. 6, 173.
    Yu, R., et al. 2000. J. Biol. Chem. 275, 2322.
    Lee, J.C., et al. 1994. Nature 372, 739.
    Citation
  • Ralf Gutzmer, et al. (2005) Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells. Journal of Immunology 5224-5232.
    		•