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472804 S-Methyl-L-thiocitrulline, Dihydrochloride - CAS 209589-59-3 - Calbiochem

472804
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
209589-59-3C₇H₁₅N₃O₂S · 2HCl

Products

Catalogue NumberPackaging Qty/Pack
472804-10MG Plastová ampulka 10 mg
Description
OverviewA cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC50 = 300 nM) compared to the endothelial enzyme (IC50 = 5.4 µM).
Catalogue Number472804
Brand Family Calbiochem®
SynonymsNδ-(S-Methyl)isothioureido-L-ornithine
References
ReferencesKrishnaswamy, N., et al. 1995. J. Biol. Chem. 270, 11103.
Furfine, E.S., et al. 1994. J. Biol. Chem. 269, 26677.
Narayanan, K., and Griffith, O.W. 1994. J. Med. Chem. 37, 885.
Product Information
CAS number209589-59-3
ATP CompetitiveN
FormWhite to off-white solid
Hill FormulaC₇H₁₅N₃O₂S · 2HCl
Chemical formulaC₇H₁₅N₃O₂S · 2HCl
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetRat neuronal nitric oxide synthase
Primary Target IC<sub>50</sub>300 nM for rat neuronal nitric oxide synthase
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
472804-10MG 04055977185331

Documentation

S-Methyl-L-thiocitrulline, Dihydrochloride - CAS 209589-59-3 - Calbiochem Certificates of Analysis

TitleLot Number
472804

References

Reference overview
Krishnaswamy, N., et al. 1995. J. Biol. Chem. 270, 11103.
Furfine, E.S., et al. 1994. J. Biol. Chem. 269, 26677.
Narayanan, K., and Griffith, O.W. 1994. J. Med. Chem. 37, 885.

Brochure

Title
Pathways and Biomarkers of Oxidative Stress
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision09-January-2017 JSW
SynonymsNδ-(S-Methyl)isothioureido-L-ornithine
DescriptionA cell-permeable, inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC50 = 300 nM) compared to the endothelial enzyme (IC50 = 5.4 µM).
FormWhite to off-white solid
Intert gas (Yes/No) Packaged under inert gas
CAS number209589-59-3
Chemical formulaC₇H₁₅N₃O₂S · 2HCl
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityH₂O (50 mg/ml)
Storage +2°C to +8°C
Hygroscopic
Do Not Freeze Ok to freeze
Toxicity Standard Handling
ReferencesKrishnaswamy, N., et al. 1995. J. Biol. Chem. 270, 11103.
Furfine, E.S., et al. 1994. J. Biol. Chem. 269, 26677.
Narayanan, K., and Griffith, O.W. 1994. J. Med. Chem. 37, 885.