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ProSep®-vA Ultra Chromatography Media

ProSep-vA chromatography media are designed to facilitate highly efficient, cost effective purification of monoclonal, polyclonal and engineered antibodies.

Overview

The ProSep-vA family of protein A affinity media is designed to facilitate highly efficient, cost effective purification of monoclonal, polyclonal and engineered antibodies. These resins are manufactured using no mammalian derived products.

ProSep®-vA Ultra media consists of protein A immobilized on porous glass that is permeated by interconnecting pores of uniform and precisely controlled size. ProSep-vA chromatography media exhibit chemical and mechanical stability over a range of conditions such as low pH, exposure to detergents, buffers of varying ionic strengths and many organic solvents.

Its matrix is optimized for large-scale production use and offers significant advantages compared with other available matrices:

  • Proven technology
  • Rigid and incompressible
  • High flow rates with low back pressure
  • No shrinkage or swelling
  • High throughput and productivity
  • Reliable scale up
  • Flexible operating conditions
  • Lower cost of operation

ProSep-vA Ultra Media

ProSep-vA Ultra media has been designed to maintain the same basic attributes of ProSep-vA High Capacity but gives an even higher binding capacity. It has been specifically optimized to address the needs of today’s higher titer, large volume fermentation feedstocks, providing high productivity and low cost of operation.

ProSep-vA Ultra Specifications
Human IgG static binding capacity: ≥ 56 mg/mL