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512731 Paromomycin Sulfate - CAS 1263-89-4 - Calbiochem

An aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity.

Paromomycin Sulfate - CAS 1263-89-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Neomycin E

512731
  
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Overview

Key Spec Table

CAS #Empirical Formula
1263-89-4C₂₃H₄₅N₅O₁₄ · H₂SO₄
Description
OverviewAn aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity. Recent NMR evidence indicates that paromomycin binding to the A-site of 16S rRNA induces a local conformational change, suggesting a mechanism for aminoglycoside action on protein translation. Also exhibits anti-protozoal properties.
Potency: ≥675 µg/mg.
Catalogue Number512731
Brand Family Calbiochem®
SynonymsNeomycin E
References
ReferencesVanLoock, M.S., et al. 1999. J. Mol. Biol. 285, 2069.
Blanchard, S.C., et al. 1998. Biochemistry 37, 7716.
Fourmy, D., et al. 1998. J. Mol. Biol. 277, 333.
Product Information
CAS number1263-89-4
FormOff-white solid
Hill FormulaC₂₃H₄₅N₅O₁₄ · H₂SO₄
Chemical formulaC₂₃H₄₅N₅O₁₄ · H₂SO₄
Structure formula ImageStructure formula Image
Quality LevelMQ100
Safety Information according to GHS
RTECSWK2320000
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 22-24/25-36/37/39-45

Do not breathe dust.
Avoid contact with skin and eyes.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +15°C to +30°C
Do not freeze Ok to freeze
Global Trade Item Number
Catalogue Number GTIN
512731 0