Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

540217 PTP LYP Inhibitor - Calbiochem

The PTP LYP Inhibitor controls the biological activity of PTP LYP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

PTP LYP Inhibitor - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (2-pyridine)(Ph)₂P-Au-Cl, HePTP Inhibitor III, PTP Inhibitor XXVIII, PTP-PEST Inhibitor

540217
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₁₇H₁₄AuClNP

Products

Catalogue NumberPackaging Qty/Pack
540217-5MG 5 mg
Description
OverviewA cell-permeable, Au(I)-phosphine complex that acts as selective inhibitor of lymphoid tyrosine phosphatase (LYP) (IC50= 1.5 µM) and has a ~10-fold selectivity for LYP over PTP-PEST, HePTP, and CD45 in both JTAg cells and primary mouse thymocytes.
Catalogue Number540217
Brand Family Calbiochem®
Synonyms(2-pyridine)(Ph)₂P-Au-Cl, HePTP Inhibitor III, PTP Inhibitor XXVIII, PTP-PEST Inhibitor
References
ReferencesKarver, M.R., et al. 2009. J. Med. Chem. 52, 6912.
Product Information
FormWhite solid
Hill FormulaC₁₇H₁₄AuClNP
Chemical formulaC₁₇H₁₄AuClNP
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥ 95% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
540217-5MG 04055977268713

Documentation

PTP LYP Inhibitor - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

PTP LYP Inhibitor - Calbiochem Certificates of Analysis

TitleLot Number
540217

References

Reference overview
Karver, M.R., et al. 2009. J. Med. Chem. 52, 6912.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision23-February-2011 RFH
Synonyms(2-pyridine)(Ph)₂P-Au-Cl, HePTP Inhibitor III, PTP Inhibitor XXVIII, PTP-PEST Inhibitor
DescriptionA cell-permeable, Au(I)-phosphine complex that acts as selective inhibitor of lymphoid tyrosine phosphatase (LYP) (IC50= 1.5 µM) and has a ~10-fold selectivity for LYP over PTP-PEST, HePTP, and CD45 in both JTAg cells and primary mouse thymocytes.
FormWhite solid
Chemical formulaC₁₇H₁₄AuClNP
Structure formulaStructure formula
Purity≥ 95% by HPLC
SolubilityDMSO (50 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesKarver, M.R., et al. 2009. J. Med. Chem. 52, 6912.