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505761 PPADS

PPADS MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: P2 Purinergic Receptor Antagonist, PPADS

505761
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
192575-19-2C₁₄H₁₀N₃Na₄O₁₂PS₂
Description
Overview

This product has been discontinued.



A selective P2 purinergic receptor antagonist that block ATP responses at both pre- and post-junctional sites (IC50 = 2.5 µM). Shown to antagonize P2x-purinoceptor-mediated responses in the rabbit urinary bladder. Acts on P2Y, but not on P2U receptors in rat mesenteric arteries. Induces a gradual decline in ATP-activated current to a steady state.

Please note that the molecular weight for this compound is batch-specific due to variable water content.
Catalogue Number505761
Brand Family Calbiochem®
SynonymsP2 Purinergic Receptor Antagonist, PPADS
References
ReferencesLi. C. 2000. J. Neurophysiol. 83, 2533.
Ralevic, V., et al. 1996. Br. J. Pharmacol. 118, 428.
Product Information
CAS number192575-19-2
FormOrange solid
Hill FormulaC₁₄H₁₀N₃Na₄O₁₂PS₂
Chemical formulaC₁₄H₁₀N₃Na₄O₁₂PS₂
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Target IC<sub>50</sub>2.5 µ
Purity≥90 by 1H NMR
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
505761 0

Documentation

PPADS MSDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Li. C. 2000. J. Neurophysiol. 83, 2533.
Ralevic, V., et al. 1996. Br. J. Pharmacol. 118, 428.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-April-2014 JSW
SynonymsP2 Purinergic Receptor Antagonist, PPADS
DescriptionA selective P2 purinergic receptor antagonist that block ATP responses at both pre- and post-junctional sites (IC50 = 2.5 µM). Shown to antagonize P2x-purinoceptor-mediated responses in the rabbit urinary bladder. Acts on P2Y, but not on P2U receptors in rat mesenteric arteries. Induces a gradual decline in ATP-activated current to a steady state.
FormOrange solid
CAS number192575-19-2
Chemical formulaC₁₄H₁₀N₃Na₄O₁₂PS₂
Structure formulaStructure formula
Purity≥90 by 1H NMR
SolubilityH₂O (100 mM)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesLi. C. 2000. J. Neurophysiol. 83, 2533.
Ralevic, V., et al. 1996. Br. J. Pharmacol. 118, 428.