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370654 PKG Inhibitor - Calbiochem

The PKG Inhibitor controls the biological activity of PKG. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

PKG Inhibitor - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Protein Kinase G Inhibitor, RKRARKE

Primary Target: PKG
370654
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₃₈H₇₄N₁₈O₁₀

Products

Catalogue NumberPackaging Qty/Pack
370654-1MG Plastová ampulka 1 mg
Description
OverviewA more specific, reversible, and substrate competitive inhibitor of protein kinase G (Ki = 86 µM) relative to protein kinase A (Ki = 550 µM). Sequence corresponds to a non-phosphorylatable analog (Ser32 to Ala32) of histone H2B (amino acids 29-35).
Catalogue Number370654
Brand Family Calbiochem®
SynonymsProtein Kinase G Inhibitor, RKRARKE
References
ReferencesGlass, D.B., et al. 1983. Biochem. J. 213, 159.
Product Information
ATP CompetitiveN
FormLyophilized
Hill FormulaC₃₈H₇₄N₁₈O₁₀
Chemical formulaC₃₈H₇₄N₁₈O₁₀
Hygroscopic Hygroscopic
ReversibleY
Sold on the basis of peptide contentY
Quality LevelMQ100
Applications
Biological Information
Primary TargetPKG
Primary Target K<sub>i</sub>86 µM against protein kinase G
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Peptide ContentY
Peptide SequenceH-Arg-Lys-Arg-Ala-Arg-Lys-Glu-OH
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
370654-1MG 04055977191646

Documentation

PKG Inhibitor - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

PKG Inhibitor - Calbiochem Certificates of Analysis

TitleLot Number
370654

References

Reference overview
Glass, D.B., et al. 1983. Biochem. J. 213, 159.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision11-January-2010 RFH
SynonymsProtein Kinase G Inhibitor, RKRARKE
DescriptionA specific, reversible, and substrate competitive inhibitor of PKG (Ki = 86 µM) relative to PKA (Ki = 550 µM). Sequence corresponds to a non-phosphorylatable analog (Ser32 to Ala32) of histone H2B (amino acids 29-35).
FormLyophilized
Chemical formulaC₃₈H₇₄N₁₈O₁₀
Peptide SequenceH-Arg-Lys-Arg-Ala-Arg-Lys-Glu-OH
Purity≥95% by HPLC
SolubilityH₂O (1 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Toxicity Standard Handling
ReferencesGlass, D.B., et al. 1983. Biochem. J. 213, 159.