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528120 PIPER - CAS 213416-70-7 - Calbiochem

A perylene-based ligand that potently inhibits human telomerase by binding to G-quadruplex DNA.

PIPER - CAS 213416-70-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: N,Nʹ-bis[2-(1-Piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic Diimide, Telomerase Inhibitor IV

Primary Target: human telomerase
528120
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
213416-70-7C₃₈H₃₆N₄O₄
Description
Overview

This product has been discontinued.



A perylene-based ligand that potently inhibits human telomerase by binding to G-quadruplex DNA. The strongest binding site for PIPER appears to be the 3′-boundary of the G-quadruplex. Can also bind non-specifically to nucleic acids. May also be useful as an antiproliferative agent.
Catalogue Number528120
Brand Family Calbiochem®
SynonymsN,Nʹ-bis[2-(1-Piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic Diimide, Telomerase Inhibitor IV
References
ReferencesHan, H., et al. 1999. Biochemistry 38, 6981.
Fedoroff, O.Y., et al. 1998. Biochemistry 37, 12367.
Product Information
CAS number213416-70-7
ATP CompetitiveN
FormDark purple solid
Hill FormulaC₃₈H₃₆N₄O₄
Chemical formulaC₃₈H₃₆N₄O₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targethuman telomerase
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20/21/22-40-68

Harmful by inhalation, in contact with skin and if swallowed.
Limited evidence of a carcinogenic effect.
Possible risks of irreversible effects.
S PhraseS: 22-36

Do not breathe dust.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful & Carcinogenic / Teratogenic
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
528120 0

Documentation

PIPER - CAS 213416-70-7 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

PIPER - CAS 213416-70-7 - Calbiochem Certificates of Analysis

TitleLot Number
528120

References

Reference overview
Han, H., et al. 1999. Biochemistry 38, 6981.
Fedoroff, O.Y., et al. 1998. Biochemistry 37, 12367.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-April-2011 RFH
SynonymsN,Nʹ-bis[2-(1-Piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic Diimide, Telomerase Inhibitor IV
DescriptionA perylene-based ligand that potently inhibits human telomerase by binding to G-quadruplex DNA. The strongest binding site for PIPER appears to be the 3'-boundary of the G-quadruplex. Can also bind non-specifically to nucleic acids. May be useful as an antiproliferative agent.
FormDark purple solid
Intert gas (Yes/No) Packaged under inert gas
CAS number213416-70-7
Chemical formulaC₃₈H₃₆N₄O₄
Structure formulaStructure formula
Purity≥95% by HPLC
Solubility5% Acetic acid (50 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Toxicity Harmful & Carcinogenic / Teratogenic
ReferencesHan, H., et al. 1999. Biochemistry 38, 6981.
Fedoroff, O.Y., et al. 1998. Biochemistry 37, 12367.